No opiates against cannabis hyperemesis syndrome

DMW - Deutsche Medizinische Wochenschrift (Impact Factor: 0.54). 02/2014; 139(8):375-7. DOI: 10.1055/s-0033-1360065
Source: PubMed


History and clinical findings:
An otherwise healthy 25-year-old patient with heavy cannabis-abuse suffered from an undiagnosed cannabis hyperemesis syndrome (CHS) over years, which characteristically was resistant to usual antiemetics. In an apparently last attempt at healing, opiates (morphine, methadone) were administrated and improved the CHS, however, this led to an at least as equally distressing and painful opiate withdrawal syndrome.

Treatment and course:
In the controlled cannabis abstinence during the 2-week inpatient treatment of opiate addiction syndrome the CHS has not recurred.

Opiates are not suited for the treatment of CHS because they are addictive and lead to respiratory depression in overdose.

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Available from: Udo Bonnet, Nov 22, 2014