Dementia in 2013: Frontotemporal lobar degeneration—building on breakthroughs

Nature Reviews Neurology (Impact Factor: 15.36). 01/2014; 10(2). DOI: 10.1038/nrneurol.2013.270
Source: PubMed


Genetic research in frontotemporal lobar degeneration (FTLD) is gaining momentum. Following the discovery of a repeat expansion in the gene C9 open reading frame 72 (C9orf72), three major genes and associated disease mechanisms and inclusion body pathologies have emerged, paving the way for personalized medicine in FTLD.

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Available from: Christine Van Broeckhoven, Jan 11, 2014
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