The Effects of Valerian Root on Hot Flashes in Menopausal Women

Iranian journal of pharmaceutical research (IJPR) (Impact Factor: 1.07). 03/2013; 12(1):217-22.
Source: PubMed


Hot flash is among the most common complaints of menopausal women, affecting their career, social activities and quality of life. This study aimed to investigate the effects of Valerian on hot flashes in menopausal women. In this double blind clinical trial, 68 menopausal women with the chief complaint of hot flash were enrolled using sampling at hand and were randomly divided into drug and placebo groups. The women in the drug group were prescribed 255 mg Valerian capsules 3 times a day for 8 weeks. The women in the placebo group were prescribed identical capsules filled with starch. Then, severity and frequency of hot flashes were measured and recorded through questionnaires and information forms in three levels (2 weeks before, four and eight weeks after the treatment). The Severity of hot flashes revealed a meaningful statistical difference pre- and post- Valerian treatment (p <0.001) while this difference was not meaningful in the placebo group. Further, the comparison of the two groups regarding the severity of hot flash after the treatment showed a meaningful statistical difference (p <0.001). Valerian has also led to a reduction of hot flash frequencies 4 and 8 weeks after the treatment (p <0.001) but this difference was not meaningful in drug like group. Valerian can be effective in treatment of menopausal hot flash and that it can be considered as a treatment of choice for reduction of hot flashes among the women who are reluctant to receive hormone therapy due to fear or any other reason.

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Available from: Parvaneh Mirabi, Jul 23, 2014
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    • "Herbal supplements are widely used for vasomotor symptoms , with varying degrees of efficacy. Among the more frequently studied are hops (Heyerick et al. 2006; Erkkola et al. 2010), red clover (Hidalgo et al. 2005; Geller et al. 2009; Lipovac et al. 2012), flaxseed (Lewis et al. 2006; Colli et al. 2012; Pruthi et al. 2012), St. John's Wort (Hypericum perforatum) (Al-Akoum et al. 2009; Abdali et al. 2010; Uebelhack et al. 2006; Briese et al. 2007), evening primrose (Oenothera biennis) (Farzaneh et al. 2013), French maritime pine bark (Pycngenol) (Yang et al. 2007; Kohama & Negami 2013); Sibiric Rhubarb (Rheum rhaponticum) (Heger et al. 2006; Kaszkin-Bettag et al. 2007; Kaszkin- Bettag et al. 2009; Hasper et al. 2009), valerian root (Valeriana officinalis) (Mirabi & Mojab 2013), Guaraná (Paullinia cupana) (Oliveira et al. 2013), and magnesium (Park et al. 2011). Summaries of these studies can be found in Additional file 1. "
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