Article

Skin and Soft Tissue Infections.

Section of Pediatric Emergency Medicine, Department of Pediatrics, Children's Hospital Colorado, University of Colorado School of Medicine, 13123 East 16th Avenue, Box B251, Aurora, CO 80045, USA. Electronic address: .
Pediatric Clinics of North America (Impact Factor: 2.2). 10/2013; 60(5):1063-1082. DOI: 10.1016/j.pcl.2013.06.011
Source: PubMed

ABSTRACT The approach to common skin and soft tissue infections (SSTIs) was previously well understood. However, the recent emergence of community-associated methicillin resistant Staphyloccocus aureus as a common pathogen has changed the epidemiology of these infections and has led clinicians to alter their practice and treatment of SSTI. This article discusses the present epidemiology of SSTI and community-acquired methicillin-resistant Staphylococcus aureus, evidence-based approach to incision and drainage, the utility of adjuvant antibiotic therapy after abscess drainage, and current antimicrobial approach to cellulitis and nondrained SSTIs. Methods to reduce transmission and recurrence of SSTI through decolonization strategies are also discussed.

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    ABSTRACT: Acute bacterial skin and skin structure infections (SSSIs) are among the most common bacterial infections in children. The medical burden of SSSIs, particularly abscesses, has increased nationwide since the emergence of community-acquired methicillin-resistant Staphylococcus aureus. SSSIs represent a wide spectrum of disease severity. Prompt recognition, timely institution of appropriate therapy, and judicious antimicrobial use optimize patient outcomes. For abscesses, incision and drainage are paramount and might avoid the need for antibiotic treatment in uncomplicated cases. If indicated, empiric antimicrobial therapy should target Streptococcus pyogenes for nonpurulent SSSIs, such as uncomplicated cellulitis, and S aureus for purulent SSSIs such as abscesses.
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