Non-apnea Sleep Disorder Increases the Risk of Periodontal Disease: A Retrospective Population-Based Cohort Study (Version 3).

Department of Oral and Maxillofacial Surgery, Buddhist Tzu Chi General Hospital, Taichung Branch, Taichung, Taiwan.
Journal of Periodontology (Impact Factor: 2.4). 09/2013; DOI: 10.1902/jop.2013.130284
Source: PubMed

ABSTRACT Aim: The aim of this study was to determine whether non-apnea sleep disorder patients with comorbidity have an increased risk of periodontal disease. Materials and Methods: Patients newly diagnosed with non-apnea sleep disorders (NA-SD) in 1997-2010 were identified as the study cohort from the Taiwan National Health Insurance (TNHI) database. For each NA-SD patient, two matched controls without sleep disorders were randomly selected for comparison. Results: The overall incidence rate ratio of severe periodontal diseases was 39% higher in the NA-SD cohort than in the without NA-SD cohort (7.93 vs. 5.69 per 1,000 person-years), with an adjusted HR of 1.36, (95% CIs = 1.30-1.43). The effect of NA-SD on the risk of severe periodontal diseases was higher in young patients, and middle-aged patients, as compared with patients over 65 years of age (≤ 35 years of age, HR = 1.13, 95% CIs = 1.04-1.24; 35-50 years of age, HR = 1.73, 95% CIs = 1.61-1.86; 50- 65 years of age, HR =1.69, 95% CI = 1.58-1.81). Conclusion: Non-apnea sleep disorder might increase the risk of periodontal disease.

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