A thymol derivative from Inula crithmoides

Institute for Organic Chemistry, Technical University of Berlin, D-1000 Berlin 12, West Germany
Phytochemistry (Impact Factor: 3.35). 24(6):1377–1378. DOI: 10.1016/S0031-9422(00)81138-3

ABSTRACT Re-investigation of the aerial parts and roots of Inula crithmoides afforded, in addition to known compounds, a new epoxythymol isovalerate. Its structure has been determined as 10-isovaleryloxy-8,9-epoxythymol-3-isovalerate

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    ABSTRACT: The chemical composition of the essential oil obtained from the aerial parts of Inula crithmoides L. was analyzed by GC and GC/MS and 22 components were identified, the major ones being p-cymene (30.1%), 1-methylethyl-trimethylbenzene (18.7%), scopoletin (15.3%) and alpha-pinene (13.1%). The antioxidant activity of the oil was evaluated by the DPPH test and 5-lipoxygenase assay. The essential oil exerted a good antioxidant activity in the protection of lipid peroxidation when compared with known antioxidants.
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