Seasonal Influenza Vaccination Coverage Rate of Target Groups in Selected Cities and Provinces in China by Season (2009/10 to 2011/12)

Centers for Disease Control and Prevention, United States of America
PLoS ONE (Impact Factor: 3.23). 09/2013; 8(9):e73724. DOI: 10.1371/journal.pone.0073724
Source: PubMed


The objectives of the survey were to identify the level of influenza vaccination coverage in China in three influenza seasons 2009/10 to 2011/12, and to find out potential predictors for seasonal influenza vaccination.
In September and October 2011, representative urban household telephone surveys were conducted in five provinces in China with a response rate of 6%. Four target groups were defined for analysis: 1) children ≤5 years old; 2) elderly persons aged ≥60 years old; 3) health care workers (persons working in the medical field) and 4) chronically ill persons.
The overall mean vaccination rate was 9.0%. Among the four target groups, the rate of vaccination of children aged ≤5 years old (mean = 26%) was highest and the rate of elderly people aged ≥60 years old (mean = 7.4%) was the lowest, while the rates of persons who suffer from a chronic illness (mean = 9.4%) and health care workers (9.5%) were similar. A subsidy for influenza vaccination, age group, health care workers, suffering from a chronic illness and living in Eastern China were independent significant predictors for influenza vaccination.
The seasonal influenza vaccination coverage rates among urban populations in selected cities and provinces in China were far below previously reported rates in developed countries. Influenza vaccination coverage rates differed widely between different target groups and provinces in China. Subsidy policy might have a positive effect on influenza vaccination rate, but further cost-effectiveness studies, as well as the vaccination rate associated factors studies are still needed to inform strategies to increase coverage.


Available from: Lei Zhou
    • "It was reported that the coverage rates of non-EPI vaccines in China were quite low—only 10% children had received PCV-7 in 2011 [9], and 26% for influenza vaccine in urban areas [10]. The demand-side factors play an important role in affecting vaccination rates. "
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    Vaccine 06/2014; 32(35). DOI:10.1016/j.vaccine.2014.06.047 · 3.62 Impact Factor
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    • "Number of cases adverted: We collected the age and province specific influenza vaccination coverage rate for seasons 2010/11 and 2011/12 from telephone surveys conducted by China CDC in 2011 (Table 1 and Table S3 in Appendix S1) [15]. We also used the annual sales of influenza vaccine to estimate the coverage rate for season 2005/06 to 2008/09, and assumed the coverage rate was the same for children in both age groups. "
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    ABSTRACT: To support policy making, we developed an initial model to assess the cost-effectiveness of potential strategies to increase influenza vaccination rates among children in China. We studied on children aged 6 months to 14 years in four provinces (Shandong, Henan, Hunan, and Sichuan), with a health care system perspective. We used data from 2005/6 to 2010/11, excluding 2009/10. Costs are reported in 2010 U.S. dollars. In comparison with no vaccination, the mean (range) of Medically Attended Cases averted by the current self-payment policy for the two age groups (6 to 59 months and 60 months to 14 years) was 1,465 (23∼11,132) and 792 (36∼4,247), and the cost effectiveness ratios were $ 0 (-11-51) and $ 37 (6-125) per case adverted, respectively. In comparison with the current policy, the incremental cost effectiveness ratio (ICER) of alternative strategies, OPTION One-reminder and OPTION Two-comprehensive package, decreased as vaccination rate increased. The ICER for children aged 6 to 59 months was lower than that for children aged 60 months to 14 years. The model is a useful tool in identifying elements for evaluating vaccination strategies. However, more data are needed to produce more accurate cost-effectiveness estimates of potential vaccination policies.
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