Iodine Insufficiency: A Global Health Problem?
Office of Dietary Supplements, National Institutes of Health, Bethesda, MD.Advances in Nutrition (Impact Factor: 4.71). 09/2013; 4(5):533-5. DOI: 10.3945/an.113.004192
As a result of collaborative efforts with international organizations and the salt industry, many developing and developed countries practice universal salt iodization (USI) or have mandatory salt fortification programs. As a consequence, the prevalence of iodine deficiency decreased dramatically. The United States and Canada are among the few developed countries that do not practice USI. Such an undertaking would require evidence of deficiency among vulnerable population groups, including pregnant women, newborns, and developing infants. Government agencies in the United States rely heavily on data from NHANES to assess the iodine status of the general population and pregnant women in particular. NHANES data suggest that pregnant women in the United States remain mildly deficient. This is important, because the developing fetus is dependent on maternal iodine intake for normal brain development throughout pregnancy. Professional societies have recommended that pregnant and lactating women, or those considering pregnancy, consume a supplement providing 150 μg iodine daily. The United States and Canada collaborate on the daily recommended intake and are also confronted with the challenge of identifying the studies needed to determine if USI is likely to be beneficial to vulnerable population groups without exposing them to harm.
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ABSTRACT: In 2001, Dietary Reference Intakes (DRIs) for iodine were set for the different gender and life-stage groups by the Institute of Medicine. Because of the serious consequences of iodine deficiency for the developing fetus and infant, there is particular interest in further understanding optimal iodine nutrition and improving the monitoring of iodine status, particularly during infancy, pregnancy, and lactation. This review discusses the basis for the current DRIs for iodine and the evidence that may be needed for considering and conducting the reevaluation of one or more of the DRIs.Advances in Nutrition 11/2013; 4(6):718-722. DOI:10.3945/an.113.004804 · 4.71 Impact Factor
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ABSTRACT: This article describes the nutritional and developmental status of young children living in Baby Houses (orphanages for children ages 0-3 years) in Kazakhstan. In 2009/2010, 308 children under age 3 years living in 10 Baby Houses were measured for height/length and weight. The Bayley Scales of Infant Development (N. Bayley, 2006) were used to assess mental and motor development. Blood was collected on a subsample to assess key nutritional factors. The World Health Organization growth charts were used to calculate Z-scores. Cut points for wasting (moderate to severe low weight for length/height growth), underweight (low weight for age), stunting (low length/height for age), development, and biomarkers used established guidelines. Most (n = 286) children had complete data on z-scores. Of these, 22.1% were experiencing wasting, 31.5% were underweight, and 36.7% had stunting. The nutritional status of the children, based on blood biomarkers, revealed that 37.1% of the children were anemic, 21.4% had low albumin, 38.1% had low vitamin D, 5.5% were iodine-deficient, and 2% had low serum zinc. One half had mild to significant mental and motor delays. Children living at these Baby Houses in Kazakhstan have substantial nutritional deficits and developmental delays. Focused attention is needed to provide a nutritionally enhanced diet and improved developmental opportunities to improve the long-term outcomes for these children. © 2014 Michigan Association for Infant Mental Health.Infant Mental Health Journal 03/2014; 35(2). DOI:10.1002/imhj.21430 · 0.61 Impact Factor
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