Article

Preoperative Asymptomatic Leucocyturia and Early Prosthetic Joint Infections in Patients Undergoing Joint Arthroplasty

Department of Orthopedics, Chinese PLA General Hospital, Beijing China.
The Journal of arthroplasty (Impact Factor: 2.37). 08/2013; 29(3). DOI: 10.1016/j.arth.2013.07.028
Source: PubMed

ABSTRACT Prosthetic joint infection (PJI) is associated with a higher mortality, morbidity and economic costs. Although it is well known that the presence of urinary tract infection (UTI) is associated with PJI, few investigations evaluated the preoperative asymptomatic leukocyturia (ASL) and the possible relationship with early PJI. We reviewed the records of 739 patients performed primary joint arthroplasty. A total of 131 patients had preoperative ASL (17.7%) and 7 of 739 patients (0.9%) had early PJI. Preoperative ASL was not confirmed as a risk factor for early PJI on the multivariate regression analysis with an adjusted OR of 1.04 (P>0.05). Therefore, it should not be considered as a reason for postponement of total joint arthroplasty.

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    ABSTRACT: SUMMARY Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the global health care industry. While a small minority of joint arthroplasties will become infected, appropriate recognition and management are critical to preserve or restore adequate function and prevent excess morbidity. In this review, we describe the reported risk factors for and clinical manifestations of PJI. We discuss the pathogenesis of PJI and the numerous microorganisms that can cause this devastating infection. The recently proposed consensus definitions of PJI and approaches to accurate diagnosis are reviewed in detail. An overview of the treatment and prevention of this challenging condition is provided.
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