A lump in an arm

Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Via dell'Istria 65/1, 34137, Trieste, Italy, .
European Journal of Pediatrics (Impact Factor: 1.89). 08/2013; 172(12). DOI: 10.1007/s00431-013-2114-4
Source: PubMed


The authors present a magnetic resonance image showing a soft tissue mass misdiagnosed as sarcoma.

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Available from: Edoardo Guida, Sep 30, 2015
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    ABSTRACT: Reports of nodular fasciitis among adults are common; however, this condition is relatively rare in the pediatric population. Its clinical and histologic characteristics are similar to malignancies such as sarcoma; thus, it is prudent for the clinician caring for children and adolescents to be aware of the possibility of its occurrence. Nodular fasciitis is a benign mesenchymal tumor. Often presenting as a rapidly enlarging soft tissue mass, clinically, it can easily be mistaken as a sarcoma or other malignancy during clinical evaluation. In addition, the pathologist may recognize its high cellularity, high mitotic index, and infiltrative borders, which, as a result, may lead to erroneous diagnosis as a malignancy. Although more frequently seen in adults, it does occur in the pediatric population and should be considered during evaluation and treatment of soft tissue masses in children and adolescents.
    Journal of Pediatric Surgery 06/2009; 44(5):e17-9. DOI:10.1016/j.jpedsurg.2009.01.047 · 1.39 Impact Factor
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    ABSTRACT: Nodular fasciitis (NF) is a reactive lesion composed of fibroblasts/myofibroblasts and most commonly found in extremities and trunk. NF has been described in the head and neck region (HNR) in 13-20% of cases. It is our impression based on consultation experience that many pathologists do not consider NF in the differential diagnosis of soft tissue masses arising in the HNR. Moreover, it is common for these lesions to be incompletely excised, leading to additional challenges in diagnosis. We describe 30 cases of NF of the HNR in order to focus attention on this frequently overlooked diagnosis. While they had the typical histologic features of NF, the lesions had a tendency for smaller size, increased skeletal muscle involvement (30%) compared to fasciitis elsewhere in the body and diffuse and strong actin expression. Follow up demonstrated one recurrence (7.1%) higher than reported elsewhere in the body. These latter features may add to the challenge in diagnosing NF in these locations.
    Journal of Cutaneous Pathology 04/2009; 36(11):1168-73. DOI:10.1111/j.1600-0560.2009.01252.x · 1.58 Impact Factor