Auto-imunidade ANCA (Anticorpo Anti-Citoplasma de Neutrófilos) positiva induzida por propiltiouracil: relato de caso e revisão da literatura
Arquivos Brasileiros de Endocrinologia & Metabologia (Impact Factor: 0.68). 01/2007; 51(1). DOI: 10.1590/S0004-27302007000100022
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ABSTRACT: Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitides are rare, but they can be triggered by chemicals, infections and drugs; among them, antithyroid drugs are common. Autoimmune disorders, such as vasculitis, are unusual, but serious complications of antithyroid therapy. Both propylthiouracil (PTU) and methimazole may induce ANCA-associated vasculitis. PTU-induced vasculitides may have different organ involvement patterns. Herein, we report four cases with ANCA-associated vasculitis with different clinical manifestations.Rheumatology International 01/2012; 33(1). DOI:10.1007/s00296-011-2280-5 · 1.63 Impact Factor
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