Presence of a multidrug-resistance mutation in an HIV-2 variant infecting a treatment-naive individual in Caio, Guinea Bissau.

Medical Research Council Laboratories, Fajara, PO Box 273, Banjul, The Gambia.
Clinical Infectious Diseases (Impact Factor: 9.42). 06/2009; 48(12):1790-3. DOI: 10.1086/599107
Source: PubMed

ABSTRACT We report the possible transmission of drug-resistant human immunodeficiency virus type 2. A 66-year-old woman from rural Guinea Bissau who had no obvious antiretroviral exposure was found to harbor a variant with the multidrug-resistance mutation Q151M. Finding this mutation among a drug-naive population presents an important public health issue that needs to be addressed for treatment to be effective.

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