Article

Strategies for early melanoma detection: Approaches to the patient with nevi

Department of Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Journal of the American Academy of Dermatology (Impact Factor: 5). 06/2009; 60(5):719-35; quiz 736-8. DOI: 10.1016/j.jaad.2008.10.065
Source: PubMed

ABSTRACT Given its propensity to metastasize and the lack of effective therapies for most patients with advanced disease, early detection of melanoma is a clinical imperative. Although there are no noninvasive techniques for the definitive diagnosis of melanoma, and the "gold standard" remains biopsy with histologic examination, a variety of modalities may facilitate early melanoma diagnosis and the detection of new and changing nevi. This article reviews the general clinical principles of early melanoma detection and various modalities that are currently available or on the horizon, providing the clinician with an up to date understanding of management strategies for their patients with numerous or atypical nevi. LEARNING OBJECTIVE: After completing this learning activity, participants should understand the clinical importance of early melanoma detection, appreciate the challenges of early melanoma diagnosis and which patients are at highest risk, know the general principles of early melanoma detection, be familiar with current and emerging modalities that may facilitate early melanoma diagnosis and the detection of new and changing nevi, know the advantages and limitations of each modality, and be able to practice a combined approach to the patient with numerous or clinically atypical nevi.

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    • "Despite the fact that early melanoma identification is linked to improved survival rates (e.g., Geller et al. 2011; Kasparian et al. 2009; Rigel and Carucci 2000), existing technology for promoting early detection appears to be fairly ineffective (e.g., Goodson and Grossman 2008; McWhirter and Hoffman- Goetz 2013; Pollitt et al. 2009). There is clearly a need for new perspectives on this problem. "
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    The Psychological record 04/2015; 65(2):323-335. DOI:10.1007/s40732-014-0108-x · 0.96 Impact Factor
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    • "It also allows reproducibility in the diagnosis, as well as the use of digital image processing techniques. There are also new encouraging techniques other than dermoscopy [4] [5] [6] [7] [8]; notwithstanding, given its facility for image acquisition, its good results and its high degree of utilization among medical experts, its use for a long period of time is ensured; in fact, dermoscopy has been recognized as the " gold standard " in the screening phase [8]. "
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    • "The use of advanced imaging technologies like optical coherence tomography [9] and confocal microscopy [10] have also been proposed by researchers to develop computer aided diagnostics systems. The advanced imagining technologies though accurate are expensive and require experienced personnel for operational procedures [11]. It is well understood that there exists a need to develop non invasive computer aided diagnostics systems to enable early detection of skin cancer melanoma utilizing non expensive imagining systems. "
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