Intrapleural streptokinase treatment for postoperative coagulated hemothorax in a newborn

Division of Neonatology, Ankara University, School of Medicine, Ankara, Turkey.
Pediatrics International (Impact Factor: 0.73). 05/2009; 51(2):307-9. DOI: 10.1111/j.1442-200X.2008.02800.x
Source: PubMed


The management of complicated parapneumonic effusions of postoperative patients by chest-tube drainage may fail because of thick viscous fluid and multiple pleural space loculations. The use of intrapleural fibrinolytic agents facilitates pleural drainage and can obviate the need for more invasive surgical interventions.1 The effectiveness of fibrinolytic treatment has been shown in instances of thoracic empyema in adults. In pediatric patients, however, examples of its use is limited. Our search of the medical literature produced no reports of fibrinolytic treatment used to drain a parapneumonic coagulated hemothorax in a newborn.2We present a case of a newborn who had developed hemothorax and was treated using streptokinase instillation through a chest tube. This is the first example of a treatment modality involving a fibrinolytic in the treatment of parapneumonic loculated effusion in a newborn.

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