Intrapleural streptokinase treatment for postoperative coagulated hemothorax in a newborn
Division of Neonatology, Ankara University, School of Medicine, Ankara, Turkey.Pediatrics International (Impact Factor: 0.73). 05/2009; 51(2):307-9. DOI: 10.1111/j.1442-200X.2008.02800.x
The management of complicated parapneumonic effusions of postoperative patients by chest-tube drainage may fail because of thick viscous fluid and multiple pleural space loculations. The use of intrapleural fibrinolytic agents facilitates pleural drainage and can obviate the need for more invasive surgical interventions.1 The effectiveness of fibrinolytic treatment has been shown in instances of thoracic empyema in adults. In pediatric patients, however, examples of its use is limited. Our search of the medical literature produced no reports of fibrinolytic treatment used to drain a parapneumonic coagulated hemothorax in a newborn.2We present a case of a newborn who had developed hemothorax and was treated using streptokinase instillation through a chest tube. This is the first example of a treatment modality involving a fibrinolytic in the treatment of parapneumonic loculated effusion in a newborn.
- [Show abstract] [Hide abstract]
ABSTRACT: The management of complicated parapneumonic effusions by conventional first-line treatment with closed intercostal tube drainage and antibiotic therapy may fail because of thick viscous fluid and multiple pleural space loculations. Intrapleural fibrinolytic treatment is a non-invasive therapeutic option. In this report, we present successful use of intrapleural streptokinase for complicated parapneumonic effusion and empyema in 2 newborns. Intrapleural fibrinolytic therapy with streptokinase appears to be a safe and effective adjunctive therapy of choice and may have significant benefit even in newborns with complicated parapneumonic effusion and empyema, and thus, it can obviate surgical intervention.Journal of Pediatric Surgery 10/2012; 47(10):e41-4. DOI:10.1016/j.jpedsurg.2012.07.034 · 1.39 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.