To investigate the risk of birth defects in offspring of female veterinarians exposed to occupational hazards such as radiation, anesthetic gases, and pesticides in veterinary practice.
The Health Risks of Australian Veterinarians project was conducted as a questionnaire-based survey of all graduates from Australian veterinary schools during the 40-year period 1960-2000.
In a multiple logistic regression controlling for the potential confounders, the study showed an increased risk of birth defects in offspring of female veterinarians after occupational exposure to high dose of radiation (taking more than 10 x-ray films per week, odds ratio: 5.73 95% CI: 1.27 to 25.80) and an increase risk of birth defects after occupational exposure to pesticides at least once per week (odds ratio: 2.39 95% CI: 0.99 to 5.77) in veterinarians exclusively working in small animal practice.
Female veterinarians should be informed of the possible reproductive effects of occupational exposures to radiation and pesticides.
"The study supported the possible association between pesticide exposure and adverse pregnancy outcome. Females involved in agricultural work reported a higher percentage of adverse outcomes of pregnancy (abortion, stillbirth and congenital anomalies) compared to females not engaged in agriculture , which agrees with other studies     . The intricate processes of the menstrual cycle, ovum production, fertilization , implantation, and growth and development of the fetus, may be particularly susceptible to low-dose exposures to endocrine disruptors. "
[Show abstract][Hide abstract] ABSTRACT: The study aimed to explore the effects of exposure to pesticides on the reproductive health and liver function of females participating in agricultural work. Blood samples were obtained from the thirty-five females (out of one hundred females of reproductive age) who were willing to donate blood. Fifty females matched for age and socio economic status were recruited as a control group to compare levels of hormones (estradiol, progesterone and follicle stimulating hormone), liver enzymes alanine aminotransferase (ALT), and aspartate aminotransferase (AST). Results showed that 53% of the females examined in this village were illiterate. Agricultural work represented 42% of the occupations encountered by females in the study. Females who helped in farming operations showed a higher incidence of adverse pregnancy outcome such as abortions and stillbirths compared to those who did not share in agricultural work. There was a significant elevation in estradiol and progesterone levels among female agricultural workers and controls. There was also elevation in serum liver enzymes (AST and ALT) in agricultural workers compared to the controls. However, there was a significant decrease in FSH level in females sharing in agricultural activities compared to the controls. It could be concluded that participation of females in agricultural activities with potential exposure to pesticides endangers their reproductive health and liver functions. Rural areas in Egypt require more attention to increase the percentage of literacy among females and raise their health awareness.
Journal of Advanced Research 04/2011; 2(2):185-189. DOI:10.1016/j.jare.2011.01.004
[Show abstract][Hide abstract] ABSTRACT: Material and methods
Analysis covered a retrospective group of 334 neonates (194 male neonates and 140 female neonates), reported to the Polish Registry of Congenital Malformations (PRCM), between 2001–2005.
The frequency of the occurrence of the urinary tract anomalies was 1.7/1000 in live newborns. No significant differences have been found between the boys and girls, regarding the duration of the pregnancy, birth weight and the occurrence of the individual urinary tract anomalies. The anomalies of the renal pelvis and ureter (0.74/1000 in live newborns) were most frequent. It has been found that 9% of their families were diagnosed with urinary tract anomalies; occurring more often in girls’ families. We also observed other organs anomalies in 5% of families. The age of the mothers was a risk factor for the occurrence of the individual anomalies (p=0.01). The renal agenesis in neonates was connected with the younger age of mothers but other congenital malformations of urinary system (Q64) were connected with the older age of mothers. The statistically significant risk factors for the occurrence of the urinary tract anomalies were: male sex (OR=1.62, p=0.002), place of residence: village (OR=1.75, p<0.001) and the older age of mothers (OR=1.12, p=0.003).
Central European Journal of Medicine 02/2011; 7(1). DOI:10.2478/s11536-011-0116-z · 0.15 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: For suppressing the development of diabetes mellitus and the onset of complications, an insulin therapy has been used for suppressing and normalizing the change of a blood glucose. In a blood glucose control by linear method such as conventional ARMA, however, there exists problem that results in the frequency of hypoglycemia. In a blood glucose prediction by a chaos theory, there also exists problem that results in the lower accuracy on behalf of the impossibility in the long-time prediction. For the improvement in the prediction accuracy of the blood glucose that looks like complicated time series, we propose a system combining the deterministic chaos theory using equal time interval, local fuzzy reconstruction method, and minimal linear model. By local fuzzy reconstruction method, we can predict the fasting blood glucose in the short term and then we can estimate the appropriate amount of insulin shot based on the measured bedtime blood glucose. Using the system, the change of blood glucose can be suppressed and normalized and the number of the insulin dosage a day can be reduced to once. Here we report the high effective result of applying the system to type II diabetes mellitus patient.
Conference proceedings: ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 02/2004; 1:750-3. DOI:10.1109/IEMBS.2004.1403267
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