PseudoViewer3: generating planar drawings of large-scale RNA structures with pseudoknots.
ABSTRACT Pseudoknots in RNA structures make visualization of RNA structures difficult. Even if a pseudoknot itself is represented without a crossing, visualization of the entire RNA structure with a pseudoknot often results in a drawing with crossings between the pseudoknot and other structural elements, and requires additional intervention by the user to ensure that the structure graph is overlap-free. Many programs such as web services prefer to obtain an overlap-free graph in one-shot rather than get a graph with overlaps to be edited. There are few programs for visualizing RNA pseudoknots, and PseudoViewer has been the almost only program that automatically draws RNA secondary structures with pseudoknots. The previous version of PseudoViewer visualizes all the known types of RNA pseudoknots as planar drawings, but visualizes some hypothetical pseudoknots as non-planar drawings.
We developed a new version of PseudoViewer for efficiently visualizing large RNA structures with any types of pseudoknots, both known and hypothetical, as planar drawings in one-shot. It is about 10 times faster than the previous algorithm, and produces a more compact and aesthetic structure drawing. PseudoViewer3 supports both web services and web applications.
The new version of PseudoViewer, PseudoViewer3, is available at (http://pseudoviewer.inha.ac.kr).
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ABSTRACT: Visualizing RNA secondary structures and pseudoknot structures is essential to bioinformatics systems that deal with RNA structures. However, many bioinformatics systems use heterogeneous data structures and incompatible software components, so integration of software components (including a visualization component) into a system can be hindered by incompatibilities between the components of the system. This paper presents an XML web service and web application program for visualizing RNA secondary structures with pseudoknots. Experimental results show that the PseudoViewer web service and web application are useful for resolving many problems with incompatible software components as well as for visualizing large-scale RNA secondary structures with pseudoknots of any type. The web service and web application are available at http://pseudoviewer.inha.ac.kr/.Nucleic Acids Research 08/2006; 34(Web Server issue):W416-22. · 8.28 Impact Factor
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ABSTRACT: RnaViz has been developed to easily create nice, publication quality drawings of RNA secondary structure. RnaViz 2 supports CT, DCSE, and RNAML input formats and improves on many aspects of the first version, notably portability and structure annotation. RnaViz is written using a hybrid programming approach combining pieces written in C and in the scripting language Tcl/Tk, making the program very portable and extensible. AVAILABILITY: Source code, binaries for Linux and MS Windows, and additional documentation are available athttp://rrna.uia.ac.be/rnaviz/Bioinformatics 02/2003; 19(2):299-300. · 5.32 Impact Factor
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ABSTRACT: The Vienna RNA secondary structure server provides a web interface to the most frequently used functions of the Vienna RNA software package for the analysis of RNA secondary structures. It currently offers prediction of secondary structure from a single sequence, prediction of the consensus secondary structure for a set of aligned sequences and the design of sequences that will fold into a predefined structure. All three services can be accessed via the Vienna RNA web server at http://rna.tbi.univie.ac.at/.Nucleic Acids Research 08/2003; 31(13):3429-31. · 8.28 Impact Factor