Laparoscopic Versus Open Subtotal Gastrectomy for Adenocarcinoma: A Case-Control Study
ABSTRACT The aim of this study is to compare technical feasibility and oncologic efficacy of totally laparoscopic versus open subtotal gastrectomy for gastric adenocarcinoma.
Laparoscopic gastrectomy for adenocarcinoma is emerging in the West as a technique that may offer benefits for patients, although large-scale studies are lacking.
This study was designed as a case-controlled study from a prospective gastric cancer database. Thirty consecutive patients undergoing laparoscopic subtotal gastrectomy for adenocarcinoma were compared with 30 patients undergoing open subtotal gastrectomy. Controls were matched for stage, age, and gender via a statistically generated selection of all gastrectomies performed during the same period of time. Patient demographics, tumor-node-metastasis (TNM) stage, histologic features, location of tumor, lymph node retrieval, recurrence, margins, and early and late postoperative complications were compared.
Tumor location and histology were similar between the two groups. Median operative time for the laparoscopic approach was 270 min (range 150-485 min) compared with median of 126 min (range 85-205 min) in the open group (p < 0.01). Hospital length of stay after laparoscopic gastrectomy was 5 days (range 2-26 days), compared with 7 days (range 5-30 days) in the open group (p = 0.01). Postoperative pain, as measured by number of days of IV narcotic use, was significantly lower for laparoscopic patients, with a median of 3 days (range 0-11 days) compared with 4 days (range 1-13 days) in the open group (p < 0.01). Postoperative early complications trended towards a decrease for laparoscopic versus open surgery patients (p = 0.07); however, there were significantly more late complications for the open group (p = 0.03). Short-term recurrence-free survival and margin status was similar between the two groups (p = not significant) with adequate lymph node retrieval in both groups.
Laparoscopic subtotal gastrectomy for adenocarcinoma is comparable to the open approach with regard to oncologic principles of resection, with equivalent margin status and adequate lymph node retrieval, demonstrating technically feasibility and equivalent short-term recurrence-free survival. Additional benefits of decreased postoperative complications, decreased length of hospital stay, and decreased narcotic use make this a preferable approach for selected patients.
- SourceAvailable from: Han Hong LeeManagement of Gastric Cancer, 07/2011; , ISBN: 978-953-307-344-6
- Surgical Endoscopy 04/2009; 24(4). DOI:10.1007/s00464-009-0697-7 · 3.31 Impact Factor
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ABSTRACT: An ongoing trial of video on demand (VOD) technology between SaskTel, TRLabs, and Canarie is trying to prove the feasibility of delivering high quality video and sound to remote destinations on the Internet. The focus has been on delivering video at speeds in excess of that necessary for real time viewing. This “Hyper” real-time VOD delivers the entire video to its destination and allows the user full local control of its playback without further network intervention. A discussion of other VOD technologies is presented for comparison. These other technologies include Internet video streaming, cable pay-per-view, non-real-time video downloads, and VHS retail/rental establishmentsWESCANEX 97: Communications, Power and Computing. Conference Proceedings., IEEE; 06/1997