Effects of therapy on haemostasis in dogs infected with Leishmania infantum, Ehrlichia canis, or both combined.
Dipartimento di Scienze Cliniche Veterinarie - Sezione di Clinica Medica, Facoltà di Medicina Veterinaria, Università degli Studi di Napoli Federico II, Via F. Delpino 1, 80137 Napoli, Italy.The Veterinary record (Impact Factor: 1.8). 05/2009; 164(14):433-4.
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ABSTRACT: Thirty naturally infected dogs were divided into three groups (10 animals each): group I (canine leishmaniosis), group II (canine ehrlichiosis) and group III (dogs co-infected by both infectious agents). Ten clinically healthy dogs were used as controls. A haematological profile was obtained and dog sera were assessed for the presence of platelet-bound IgM and IgG antibodies (PBIgM, PBIgG) using flow cytometry. Eight of the naturally co-infected dogs (80%), five of the leishmaniotic dogs (50%) and six of the ehrlichiotic dogs (60%) had detectable levels of platelet-bound antibodies (PBIg). No PBIg were observed in the control group. The hypothesis that Leishmania and Ehrlichia co-infection could more severely affect the immune response of infected dogs is discussed.The Veterinary Journal 04/2010; 188(1):118-21. · 2.42 Impact Factor
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