Article

Bullous pemphigoid is a rare paraneoplastic syndrome in patients with renal cell carcinoma.

Department of Urology, Ruhr-University Bochum, Marienhospital Herne, Germany.
Scandinavian Journal of Urology and Nephrology (Impact Factor: 1.01). 04/2009; 43(4):334-6. DOI: 10.1080/00365590902811545
Source: PubMed

ABSTRACT Renal cell carcinoma is associated with paraneoplastic syndromes in up to 40% of cases. Dermatological manifestations are rare. A case of a bullous pemphigoid as a paraneoplastic symptom was diagnosed in a 52-year-old patient with a partially sarcomatoid papillary renal cell carcinoma.

0 Bookmarks
 · 
104 Views
  • [Show abstract] [Hide abstract]
    ABSTRACT: The case is reported of a 75-year-old man with bullous pemphigoid that was resistant to conventional treatment with prednisone and azathioprine. A hypernephroma was discovered and surgically excised, whereafter the skin lesions healed completely without any other therapeutic measures being taken.
    Der Hautarzt 03/1988; 39(2):121. · 0.50 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Renal cell carcinoma is unique among the genitourinary malignancies in that close to one third of affected patients show signs and symptoms of a paraneoplastic syndrome. The paraneoplastic syndromes associated with renal cell carcinoma range from those manifesting in constitutional symptoms (ie, fever, cachexia, and weight loss) to those that result in specific metabolic and biochemical abnormalities (ie, hypercalcemia, nonmetastatic hepatic dysfunction, amyloidosis, etc). The presence of a paraneoplastic syndrome in a patient with renal cell carcinoma is neither a marker of metastatic disease nor necessarily indicative of a poor prognosis. The importance of understanding the pathophysiology and biology behind the many paraneoplastic syndromes associated with renal cell carcinoma lies in the fact that the presence of these protean symptoms may be the initial presentation of either primary or recurrent disease. In this review, we will describe the proposed mechanisms of action of the many paraneoplastic syndromes associated with renal cell carcinoma as well as outline the clinical evaluation and treatment options currently available for these noteworthy disorders.
    Reviews in urology 02/2002; 4(4):163-70.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Renal cell carcinoma associated paraneoplastic symptoms include constitutional symptoms as well as specific metabolic and biochemical abnormalities. These are present in up to 40% of patients with renal cell carcinoma during the course of the disease. This report provides information on the most common manifestations and their therapy; some rare variants are also mentioned. The importance of paraneoplasia lies partly in the fact that paraneoplastic symptoms may be the precursor of either primary or recurrent disease. The presence of paraneoplastic manifestations does not necessarily imply a poor prognosis or metastatic disease.
    Der Urologe 02/2007; 46(1):45-8. · 0.46 Impact Factor