Article

Infernal 1.0: inference of RNA alignments.

HHMI Janelia Farm Research Campus, Ashburn, VA 20147, USA.
Bioinformatics (Impact Factor: 4.62). 04/2009; 25(10):1335-7. DOI: 10.1093/bioinformatics/btp157
Source: PubMed

ABSTRACT INFERNAL builds consensus RNA secondary structure profiles called covariance models (CMs), and uses them to search nucleic acid sequence databases for homologous RNAs, or to create new sequence- and structure-based multiple sequence alignments. AVAILABILITY: Source code, documentation and benchmark downloadable from http://infernal.janelia.org. INFERNAL is freely licensed under the GNU GPLv3 and should be portable to any POSIX-compliant operating system, including Linux and Mac OS/X.

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