[Thyroid metastasis of lung cancer and abnormal thyroid function--a case report].

Service de pneumologie, CHU de Strasbourg, 1, place de l'Hôpital, 67000 Strasbourg, France.
Revue de Pneumologie Clinique (Impact Factor: 0.25). 03/2009; 65(1):27-31. DOI: 10.1016/j.pneumo.2008.08.003
Source: PubMed


The thyroid gland is a very rare location of metastasis and the metastatic involvement of the thyroid is mostly asymptomatic. The authors report one of the first cases of pulmonary adenocarcinoma associated with painful metastatic involvement of the thyroid gland. Temporary hyperthyroidism was noted, followed, two months later, by clinically and biologically proven hypothyroidism with positive antithyroglobulin antibodies. The suspect goiter was detected by diffuse hyperfixation on 18-FDG PET Scan and the ultrasonography revealed two hypoechogenic nodules. The fine needle biopsy confirmed the metastatic origin of these nodules. The evolution after five cycles of chemotherapy by cisplatine and docetaxel was marked by a complete regression of the thyroid metastasis and an improvement in the thyroid function.

12 Reads
  • [Show abstract] [Hide abstract]
    ABSTRACT: Thyroid metastasis of solid tumors is rare and often asymptomatic. Differential diagnosis with malignant thyroid tumor is difficult. We report a 65-year-old man who presented with a solitary intrathoracic thyroid nodule of the left lobe, inaccessible to fine needle biopsy. His past medical history was remarkable for a nephrectomy for a kidney clear cell carcinoma one year before. The PET-scan did not show any abnormal fixation. A left lobo-isthmectomy was performed. Histologic examination revealed an intrathyroid metastasis of kidney carcinoma.
    La Revue de Médecine Interne 03/2011; 32(3):e37-9. DOI:10.1016/j.revmed.2010.04.016 · 1.07 Impact Factor

Similar Publications