Selective adhesion of nanoparticles to inflamed tissue in gastric ulcers.
Laboratory of Pharmaceutical Engineering (EA3924), School of Medicine and Pharmacy, University of Franche-Comté, Place Saint Jacques, 25000, Besançon, France.Pharmaceutical Research (impact factor: 4.09). 06/2009; 26(5):1285. DOI:10.1007/s11095-009-9872-8 pp.1285
Article: Nanomedicine in GI.[show abstract] [hide abstract]
ABSTRACT: Recent advances in nanotechnology offer new hope for disease detection, prevention, and treatment. Nanomedicine is a rapidly evolving field wherein targeted therapeutic approaches using nanotechnology based on the pathophysiology of gastrointestinal diseases are being developed. Nanoparticle vectors capable of delivering drugs specifically and exclusively to regions of the gastrointestinal tract affected by disease for a prolonged period of time are likely to significantly reduce the side effects of existing otherwise effective treatments. This review aims at integrating various applications of the most recently developed nanomaterials that have tremendous potential for the detection and treatment of gastrointestinal diseases.AJP Gastrointestinal and Liver Physiology 12/2010; 300(3):G371-83. · 3.43 Impact Factor
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