Clinically unapparent melanocytic nevi on the prepuce

Department of Anatomical Pathology, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain.
Journal of Cutaneous Pathology (Impact Factor: 1.58). 05/2009; 36(4):444-7. DOI: 10.1111/j.1600-0560.2008.01070.x
Source: PubMed


Melanocytic nevi from the genitalia are uncommon. Nevi on the vulva are much better described than nevi on male genitalia. To our knowledge, a systematic study of preputial melanocytic nevi has not been reported.
To investigate the frequency of clinically unapparent melanocytic nevi on a series of preputial excisions.
We undertook a prospective histologic study of the prepuce obtained in a series of 372 consecutive circumcisions for phimosis performed during the period between January 2000 and December 2002.
Incidental preputial melanocytic nevi were detected in four (1.1%) patients. Lesions were dermal in nature, most of them showed pigment in superficial dermal nests and had pseudovascular spaces. There were no cytologic atypia, mitotic figures, architectural disorder or inflammatory infiltrate. The mean (standard deviation, SD) of the maximum diameter was 1.08 (0.85) mm (range 0.34-1.79 mm). The mean age (SD) of the patients was 41.5 (4.95) years (range 29-58).
Incidental melanocytic nevi, although uncommonly, can be observed in the prepuce. They are detected in adults and may pose a diagnostic challenge when they are detected in the setting of concurrent malignant melanoma.

9 Reads
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Penile tumours are an important problem of male health affecting physical, mental and sexual health. Penile tumours can be subdivided into benign and malignant lesions. Their knowledge is important to prevent mutilating surgery in benign lesions. On the other hand, early recognition of malignancies is important for improved prognosis, and preservation of function. The most important tumour by epidemiology and prognosis is penile cancer. In contrast, malignant melanoma, sarcomas and lymphomas are rare. Clinical symptoms, histopathology and treatment options are discussed. Best possible treatment needs an interdisciplinary approach.
    Journal of the European Academy of Dermatology and Venereology 03/2014; 28(10). DOI:10.1111/jdv.12491 · 2.83 Impact Factor