In order to evaluate the differences and similarities between the liposoluble constituents in Cynomorium songaricum populations, stem liposoluble constituents in five populations of C. songaricum collected from three different geographic regions and four different hosts were obtained by solvent extraction and analyzed by GC-MS. Cluster analysis of the percentage composition of 80 compounds showed differences in chemical composition which were related to the geographic origin rather than the host. Hexadecanoic acid was the most abundant compound in the essential oils of C. songaricum from hosts Nitraria sibirica and Nitraria tanguticum. Whereas (Z)-9-octadecenoic acid was accumulated in the oils of C. songaricum from Zygophyllum xanthoxylum and Peganum harmala. Four of the five populations had characteristic components, which were specific to each population.
"(Z)-9-octa- decenoic acid was accumulated in the oils of C. songaricum from Zygophyllum xanthoxylum and Peganum harmala. Four of the five populations had characteristic components which were specific to each population (Zhou et al., 2009). Sabra et al. (2012) investigated that the characteristic phytochemical profile of caffeic acid derivatives, alkamides and/or ketones was not affected by salinity. "
[Show abstract][Hide abstract] ABSTRACT: The fatty acids contents of Peganum harmala plant as a result of hexane extraction was analyzed using GC–MS. The saturated fatty acids composition of harmal plant were tetradecanoic, pentadecanoic, tridecanoic, hexadecanoic, heptdecanoic and octadecanoic, while the saturated fatty acid derivatives were 12-methyl tetradecanoic, 5,9,13-trimethyl tetradecanoic and 2-methy octadecanoic. The most abundant fatty acid was hexadecanoic with concentration 48.13% followed by octadecanoic with concentration 13.80%. There are four unsaturated fatty acids called (E)-9-dodecenoic, (Z)-9-hexadecenoic, (Z,Z)-9,12-octadecadienoic and (Z,Z,Z)-9,12,15-octadecatrienoic. The most abundant unsaturated fatty acid was (Z,Z,Z)-9,12,15-octadecatrienoic with concentration 14.79% followed by (Z,Z)-9,12-octadecadienoic with concentration 10.61%. Also, there are eight non-fatty acid compounds 1-octadecene, 6,10,14-trimethyl-2-pentadecanone, (E)-15-heptadecenal, oxacyclohexadecan-2one, 1,2,2,6,8-pentamethyl-7-oxabicyclo[4.3.1]dec-8-en-10-one, hexadecane-1,2-diol, n-heneicosane and eicosan-3-ol.
Saudi Journal of Biological Sciences 04/2015; 40. DOI:10.1016/j.sjbs.2015.04.013 · 1.26 Impact Factor
"Extracted from its stem is a widely used Chinese herbal remedy for treating sexual dysfunction, infertility, deficient kidney function, and lumbar weakness, as well as for facilitating catharsis, as described in ancient Chinese medical books. Chemical components identified in CS extracts include organic acids, triterpenes, flavonoids, polysaccharide, and steroidal compounds [14–16]. A recent report described the potent effect of CS extracts on promoting spermatogenesis in rat testes as mediated through glial cell-derived neurotrophic factor (GDNF) stimulation, supporting the traditional utilization of CS for male sexual dysfunction . "
[Show abstract][Hide abstract] ABSTRACT: Aging is highly correlated with the progressive loss of physiological function, including cognitive behavior and reproductive capacity, as well as an increased susceptibility to diseases; therefore, slowing age-related degeneration could greatly contribute to human health.
Rupr. (CS) is traditionally used to improve sexual function and treat kidney dysfunction in traditional Chinese medicine, although little is known about whether CS has effects on longevity. Here, we show that CS supplementation in the diet extends both the mean and maximum lifespan of adult female flies. The increase in lifespan with CS was correlated with higher resistance to oxidative stress and starvation and lower lipid hydroperoxides (LPO) levels. Additionally, the lifespan extension was accompanied by beneficial effects, such as improved mating readiness, increased fecundity, and suppression of age-related learning impairment in aged flies. These findings demonstrate the important antiaging effects of CS and indicate the potential applicability of dietary intervention with CS to enhance health and prevent multiple age-related diseases.
Evidence-based Complementary and Alternative Medicine 07/2012; 2012(10):735481. DOI:10.1155/2012/735481 · 1.88 Impact Factor
"Most of the studies on biological properties of C. coccineum have been carried out with aqueous and ethanol extracts (Abd El- Rahman et al., 1999; Abdel-Magied et al., 2001; Al-Qarawi et al., 2000; Ikram et al., 1978; Rached et al., 2010). An oil has been recently isolated by extraction of the stems of Cynomorium songaricum (Zhou et al., 2009), a root-parasitic plant species, used in traditional Chinese medicinal materials, closely related to C. coccineum (Dharmananda, 2011). In literature, there are also a few examples on the use of C. coccineum as a remedy of emergency food during the famine (famine foods). "
[Show abstract][Hide abstract] ABSTRACT: Cynomorium coccineum L. is a non-photosynthetic plant, spread over Mediterranean countries, amply used in traditional medicine. We investigated the composition and effect on intestinal Caco-2 cell viability and lipid profile of fixed oil obtained from dried stems of the plant. Oil isolation has been performed by supercritical fractioned extraction with CO(2). (13)C NMR spectroscopy has been used to study the molecular composition of oil lipids; fatty acid composition was identified using GC and HPLC techniques. The fixed oil was composed mainly by triacylglycerols and derivates. The main fatty acids were 18:1 n-9 (38%), 18:2 n-6 (20%), 16:0 (15%), and 18:3 n-3 (10.8%). The oil showed a significant in vitro inhibitory effect on the growth of colon cancer undifferentiated Caco-2 cells. Moreover, cell viability, lipid composition, and lipid peroxidation were measured in intestinal epithelial cells (differentiated Caco-2 cells) after 24h incubation with fixed oil. The oil did not show a toxic effect on colon epithelial cell viability but induced a significant change in fatty acid composition, with a significant accumulation of the essential fatty acids 18:3 n-3 and 18:2 n-6. The results showed remarkable biological activity of Maltese mushroom oil, and qualify it as a potential resource for food/pharmaceutical applications.
Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association 07/2012; 50(10):3799-807. DOI:10.1016/j.fct.2012.07.003 · 2.90 Impact Factor
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