Unexplained syncope, Brugada-like ECG and minimal structural right ventricular abnormalities: which is the right diagnosis?
ABSTRACT We describe a 65-year-old man with unexplained syncope, Brugada ECG pattern and right ventricular abnormalities. To reach a diagnosis of Brugada syndrome, a variety of diseases have to be excluded. This case report shows how difficult the differential diagnosis is, particularly with arrhythmogenic right ventricular cardiomyopathy, after documentation of minimal structural RV abnormalities; invasive examination may be required. In this case, three-dimensional electroanatomical bipolar voltage mapping revealed a scar area in the right ventricle in the absence of clear-cut kinetic abnormalities, but the sensitivity of this method and specificity in patients without confirmed arrhythmogenic right ventricular cardiomyopathy have not been defined.
- SourceAvailable from: Bortolo MartiniSudden Death, Edited by Jashin Wu, Jessica WU, 01/2013: chapter A RARE LETHAL SYNDROME IN SEARCH OF ITS IDENTITY: SUDDEN DEATH, RIGHT BUNDLE BRANCH BLOCK AND ST SEGMENT ELEVATION: pages 1-39; Nova Biomedical New York., ISBN: 978-1-62618-844-0
- Journal of Cardiovascular Medicine 07/2009; 10(10):819. DOI:10.2459/JCM.0b013e32832e0b06 · 1.51 Impact Factor
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ABSTRACT: Both Brugada syndrome (BrS) and arrhythmogenic right ventricle dysplasia/cardiomyopathy (ARVD/C) can cause repolarization abnormalities in right precordial leads and predispose to sudden cardiac death (SCD) due to ventricular arrhythmias. Although there is controversy over whether BrS is distinct from ARVD/C, it is believed that both are different clinical entities with respect to both the clinical presentation and the genetic predisposition. The coexistence of these two relatively rare clinical entities is also reported, but, some hypothesized that it is more possible that disease of the right ventricular muscle might accentuate the Brugada electrocardiographic pattern. In clinic practice, there may be cases where the dividing line is not so clear. We report a 33-year-old male presenting with recurrent syncope, who has a peculiar pattern of coved-type ST-segment elevation (ST-SE) with epsilon-like wave in right precordial leads.Annals of Noninvasive Electrocardiology 08/2009; 14(3):305-8. DOI:10.1111/j.1542-474X.2009.00302.x · 1.08 Impact Factor