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Quality of life in children and adolescents with obsessive-compulsive disorder: base rates, parent-child agreement, and clinical correlates. Social Psychiatry and Psychiatric Epidemiology, 44(11), 935-942

Department of Behavioral Sciences, Arkansas Tech University, Russellville, AR 72801, USA.
Social Psychiatry (Impact Factor: 2.58). 04/2009; 44(11):935-42. DOI: 10.1007/s00127-009-0013-9
Source: PubMed

ABSTRACT The presence of obsessive-compulsive disorder (OCD) has been linked to decreased quality of life (QoL) among adults, yet little is known about the impact of OCD on QoL in pediatric patients. Sixty-two youth with OCD and their parent(s) were administered the Children's Yale-Brown Obsessive Compulsive Scale following a clinical interview. Children completed the Pediatric Quality of Life Inventory and parents completed the Pediatric Quality of Life Parent Proxy Inventory and Child Behavior Checklist. QoL scores for OCD patients were significantly lower than for healthy controls, but similar to QoL in a general psychiatric sample on the majority of domains. Parent-child agreement on QoL was moderate to strong across age groups. Results indicate that, in youth with OCD, QoL is reduced relative to healthy controls, related to OCD symptom severity per parent-report, and are strongly predicted by the presence of comorbid externalizing and internalizing symptoms.

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    • "The PedsQL Total Score provides a metric of overall child-rated quality of life. Extensive validity and reliability data have been published across multiple clinical presentations in support of the PedsQL (e.g., Varni and Burwinkle, 2006; Lack et al., 2009). Multidimensional Anxiety Scale for Children (MASC; March et al., 1997). "
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    Psychiatry Research 12/2014; 225(3). DOI:10.1016/j.psychres.2014.11.045 · 2.68 Impact Factor
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    • "Comorbid depression occurs in 35–40% of youth with OCD (Swedo et al., 1989), with increased severity of OCD being linked to worse depressive symptoms (Canavera et al., 2010; Langley et al., 2010; Peris et al., 2010). Depression exacerbates functional impairments and quality of life (Lack et al., 2009), and lead to complication of treatment outcomes for youth with OCD (Storch et al., 2008). Comorbid anxiety is even more prevalent than depression, occurring in 50–77% of youth with OCD (Ivarsson et al., 2008; Contents lists available at ScienceDirect journal homepage: www.elsevier.com/locate/jad "
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    • "Obsessive–compulsive disorder (OCD) is a chronic and disabling neuropsychiatric disorder that is characterized by the presence of recurrent, distressing, and disabling obsessions and/or compulsions (American Psychiatric Association 2000). Obsessive–compulsive disorder tends to have its onset during childhood or adolescence (Berg et al. 1989), has a lifetime prevalence of 1–2 % (Douglass et al. 1995; Zohar 1999), and is associated with marked impairments in psychosocial, academic, and family functioning (Lack et al. 2009; Piacentini et al. 2003). Additionally , pediatric OCD is often accompanied by comorbid conditions including tic, anxiety, mood and behavioral disorders, which may further complicate course of illness and treatment (Geller et al. 1998, 2000; Storch et al. 2008). "
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