Article

Age-dependent reference intervals for measured bioavailable testosterone on the Siemens Advia Centaur: ethnicity-specific values not necessary for South Asians.

Department of Pathology and Laboratory Medicine, St. Paul's Hospital and the University of British Columbia, Vancouver, BC, Canada.
Clinical biochemistry (impact factor: 2.02). 03/2009; 42(9):922-5. DOI:10.1016/j.clinbiochem.2009.02.011 pp.922-5
Source: PubMed

ABSTRACT To determine reference intervals for bioavailable testosterone for the Siemens Centaur analyzer and to assess the need for ethnicity-specific ranges for total testosterone and/or bioavailable testosterone in South Asians.
Testosterone was measured before and after ammonium sulphate precipitation on specimens collected from a small cohort of healthy male South Asians and Europeans.
Inter-ethnicity differences in BioT and TT were not significant. Age-specific BioT reference intervals are reported.
Ethnicity-specific TT and BioT reference intervals for South Asians do not appear necessary.

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Keywords

Age-specific BioT reference intervals
 
ammonium sulphate precipitation
 
bioavailable testosterone
 
BioT reference intervals
 
ethnicity-specific ranges
 
Europeans
 
healthy male South Asians
 
reference intervals
 
Siemens Centaur analyzer
 
small cohort
 
South Asians