Pregnant Patients Suspected of Having Acute Appendicitis: Effect of MR Imaging on Negative Laparotomy Rate and Appendiceal Perforation Rate
ABSTRACT To investigate the effect of magnetic resonance (MR) imaging on the negative laparotomy rate (NLR) and the perforation rate (PR) in pregnant patients suspected of having acute appendicitis (AA) and to assess the need for computed tomography (CT) in this setting.
The data of 148 consecutive pregnant patients (mean age, 29 years; age range, 15-42 years; mean gestational age, 20 weeks; gestational age range, 4-37 weeks) who were clinically suspected of having AA and examined with MR imaging between March 2002 and August 2007 were retrospectively analyzed in an institutional review board-approved HIPAA-compliant protocol. One hundred forty patients underwent ultrasonography (US) before MR imaging. The clinical and laboratory data and the findings of the initial US and MR image interpretations were recorded and analyzed at Student t and Fisher exact testing. The NLR and PR were calculated.
Fourteen (10%) patients had AA, and perforation occurred in three (21%) of them. US results were positive for AA in five (36%) patients with proved AA. MR results were positive in all 14 patients with AA. MR results were negative in 125 of the 134 patients without AA; there were nine false-positive cases (two positive, seven inconclusive). Among the patients without AA, the normal appendix could be visualized on US images in less than 2% (two of 126) of cases and on MR images in 87% (116 of 134) of cases (P < .0001). Twenty-seven (18%) patients underwent surgical exploration, and eight of them had negative laparotomy results, yielding an NLR of 30% and a PR of 21% (three of 14 patients). Only four (3%) patients underwent CT.
For pregnant patients clinically suspected of having AA, use of MR imaging yields favorable combinations of NLR and PR compared with previously reported values. The radiation exposure associated with CT examination can be avoided in most cases.
- SourceAvailable from: Sanjay HarrisonAppendicitis - A Collection of Essays from Around the World, 01/2012; , ISBN: 978-953-307-814-4
- [Show abstract] [Hide abstract]
ABSTRACT: The purpose of this article was to determine the usefulness of multiplanar and 3-dimensional (3D) reconstructions of computed tomographic (CT) data from scans performed for maternal indications for visualizing fetal anatomy and estimating gestational age. Eighteen pregnant patients who had abdominopelvic CT scanning performed for maternal indications formed the study group. Two independent reviewers created multiplanar and 3D-reconstructed images of the fetus from these CT scans and analyzed them for fetal anatomy and gestational age. Fetal dose estimates were also obtained. Computed tomographic fetal biometry generally agreed well with ultrasound estimates. Computed tomographic and ultrasound estimates were within 3 to 4 weeks of each other 95% of the time for the 2 reviewers. Pearson correlation coefficients were 0.989 for reviewer 1 and 0.985 for reviewer 2. Fetal anatomic survey revealed that it was easier to see bones and fluid-filled structures such as the stomach and urinary bladder than intracranial, intrathoracic, and intra-abdominal soft tissue structures. Estimated fetal dose was 28.5 (10.7) mGy using the Imaging Performance Assessment of CT Scanner calculator and 23.7 (7.7) mGy when taking maternal perimeter and fetal depth into account with the method of Angel et al. It is technically feasible to produce clinically useful images of the fetus using standard multiplanar reconstructions and 3D algorithms already in place for CT scanning. As CT scans continue to be performed under certain circumstances, particularly the emergency department setting, evaluation of maternal CT scans for potentially useful information about the fetus such as gestational age and gross anatomic survey can be obtained at estimated fetal radiation doses much lower than the actionable level of 150 mGy.Journal of computer assisted tomography 01/2011; 35(4):446-53. DOI:10.1097/RCT.0b013e3182206f40 · 1.60 Impact Factor