Cystic clear cell myoepithelioma of the parotid gland. A case report

Department of Pathology, Ministry of Health, Ankara Training and Research Hospital, Ankara, Turkey.
Oral and Maxillofacial Surgery 03/2009; 13(1):45-8. DOI: 10.1007/s10006-009-0145-9
Source: PubMed


BACKGROUND: Myoepitheliomas of salivary glands are generally encapsulated, slowly growing asymptomic solid masses in which more than 50% are seen in the parotid gland. Cystic myoepitheliomas are very rare. CASE REPORT: We present an 80-year-old man with a cystic mass in the right parotid gland that had undergone superficial parotidectomy. In gross examination, a mass containing a large cyst was observed. Microscopically, tumor consisted of clear cells and small cuboidal cells, forming tubules in a hyalinized stroma. Immunohistochemically, clear cells were immunoreactive for S100 and smooth muscle actin. Cuboidal cells were positive for cytokeratin. Diagnostic and differential diagnostic criteria were discussed under the light of the current literature.

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    • "Cystic change seen in our case 2 is peculiar to the clear cell type of myoepithelioma as suggested by previous reports of cystic changes in two such tumors from the parotid[89] and one from the hard palate.[4] "
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    ABSTRACT: Myoepitheliomas are rare, benign neoplasms affecting predominantly parotid gland and to a lesser extent minor salivary glands. In this article we have reported three cases with different histomorphological patterns. Two cases are from oral cavity and one from sinonasal tract, a very rare location. We have discussed different histomorphological patterns of myoepitheliomas, which at times possesses a real diagnostic dilemma to a pathologist. Along with its morphology, immunohistochemical profile and clinical behavior are discussed in detail with relevant review of literature.
    Journal of Oral and Maxillofacial Pathology 05/2013; 17(2):257-60. DOI:10.4103/0973-029X.119748
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    ABSTRACT: Myoepitheliomas of the parotid glands are very rare in the pediatric population. Only a few cases of myoepitheliomas of the salivary glands have been reported in children. They have some similar features with pleomorphic adenoma. However, they may be malignant and infiltrate locally. Hence, histopathologic examination should be considered to differentiate these tumors. The treatment of myoepitheliomas is complete removal of the tumor. We report a child with myoepithelioma of the parotid gland and review the related literature.
    Journal of Pediatric Surgery 07/2010; 45(7):E5-7. DOI:10.1016/j.jpedsurg.2010.04.009 · 1.39 Impact Factor
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    ABSTRACT: Myoepitheliomas are extremely rare benign neoplasms of salivary glands. They represent 1-1.5% of all salivary gland tumors. They occur, principally, in the parotid gland and infrequently in minor salivary glands. There are distinct histological and immunohistochemical characteristics of the tumor which aid in the diagnosis. Myoepithelioma of the palate is uncommon and only a limited number of cases has been reported in the English literature. Herein, a case of plasmacytoid type of myoepithelioma of the palate in an adult female is presented along with review of the literature.
    Head and Neck Pathology 12/2010; 5(2):154-8. DOI:10.1007/s12105-010-0231-1
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