Do elderly edentulous patients with a history of periodontitis harbor periodontal pathogens?: Periodontal pathogens in elderly subjects

University of Taubaté, São Paulo, Brazil.
Clinical Oral Implants Research (Impact Factor: 3.12). 06/2010; 21(6):618-623. DOI: 10.1111/j.1600-0501.2009.01892.x

ABSTRACT The presence of periodontal pathogens in the oral cavity may impact implant survival. Therefore, this study aimed to determine the prevalence of Campylobacter rectus, Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Prevotella intermedia, Tannerella forsythia, Treponema denticola, Eikenella corrodens and Parvimonas micra in a specific elderly population with a history of periodontitis who have never worn dentures.
Thirty dentate subjects (mean age 61.7+/-7.05 years) and 30 edentulous subjects (mean age 65.8+/-8.05 years) were included in this cross-sectional study. Microbiological samples of cheek mucosa and the dorsum of the tongue were taken from all subjects. In addition, sulcus samples were taken from the dentate group. All samples were analysed using a bacterial DNA-specific polymerase chain reaction.
All the pathogens studied were detected in dentate and edentulous subjects. When cheek and tongue samples were combined, C. rectus, A. actinomycetemcomitans and E. corrodens presented with a similar prevalence in both groups, whereas the other species were more prevalent specifically in the dentate group (P<0.05). In dentate subjects, P. intermedia and T. denticola were present in higher frequencies in the cheek mucosa (26.67% and 66.67%, respectively), whereas P. gingivalis and T. forsythia were more prevalent in the tongue samples (26.67% and 56.67%, respectively).
Periodontal pathogens may persist in the oral cavity of edentulous subjects who have had periodontal disease, even 1 year after the extraction of all teeth and in the absence of other hard surfaces in the mouth.

1 Follower
  • [Show abstract] [Hide abstract]
    ABSTRACT: Although peri-implant bone loss is one of the parameters included in the criteria for determining implant success, its prevention is of vital importance. The goal of this article is to assess the factors that affect peri-implant bone loss.
    Clinical Oral Implants Research 06/2014; DOI:10.1111/clr.12416 · 3.12 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: AimThe aim of the study was to evaluate the effect of full-mouth tooth extraction on the oral microflora, with emphasis on the presence and load of Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis.Material and methodsAdult patients (n=30), with moderate to advanced periodontitis and scheduled for full-mouth tooth extraction, were consecutively selected. Prior to and 1 and 3 months after full-mouth tooth extraction saliva, tongue, buccal and gingival mucosa and subgingival plaque/prosthesis samples were obtained. Aerobic and anaerobic culture techniques and quantitative real-time polymerase chain reaction (qPCR) were employed for the detection of oral pathogens.ResultsFull-mouth tooth extraction resulted in reduction below detection level of A. actinomycetemcomitans and P. gingivalis in 15 of 16 and 8 of 16 previously positive patients using culture techniques and qPCR, respectively. Those patients remaining qPCR positive showed a significant reduction in load of these bacteria.Conclusion Full-mouth tooth extraction significantly changes the oral microflora. These changes include reduction of A. actinomycetemcomitans and P. gingivalis, frequently to levels below detection threshold. In some patients A. actinomycetemcomitans and P. gingivalis can persist in the edentulous oral cavity up to three months after full-mouth tooth extraction.This article is protected by copyright. All rights reserved.
    Journal Of Clinical Periodontology 07/2014; DOI:10.1111/jcpe.12297 · 3.61 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: This review article describes the microbiota associated with periodontal disease in Latin America. This vast territory includes 22 nations, which show great ethnic diversity, with large groups of White people, Black people, Mestizo people and Native people. Widespread poverty and limited access to education and health-care services, including periodontal care, are prominent predisposing factors for destructive periodontal disease in Latin America. Black people and Mestizo people seem to have particularly severe periodontal disease and are frequently colonized by the major periodontal pathogens Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. The 'red complex' bacterial pathogens and A. actinomycetemcomitans predominate in chronic and aggressive periodontitis, but gram-negative enteric rods and herpesviruses can also play important periodontopathic roles in Latin America. The key to minimizing the risk of periodontal disease is control of the pathogens, and new low-cost periodontal treatments deserve serious consideration in Latin America. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
    Periodontology 2000 02/2015; 67(1):58-86. DOI:10.1111/prd.12074 · 3.00 Impact Factor


Available from
Nov 12, 2014