Article

Intercellular communication in atherosclerosis.

Department of Internal Medicine, Division of Cardiology, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.
Physiology (Bethesda, Md.) (impact factor: 7.95). 03/2009; 24:36-44. DOI:10.1152/physiol.00036.2008 pp.36-44
Source: PubMed

ABSTRACT Cell-to-cell communication is a process necessary for physiological tissue homeostasis and appears often altered during disease. Gap junction channels, formed by connexins, allow the direct intercellular communication between adjacent cells. After a brief review of the pathophysiology of atherosclerosis, we will discuss the role of connexins throughout the different stages of the disease.

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Keywords

adjacent cells
 
different stages
 
direct intercellular communication
 
Gap junction channels
 
pathophysiology