Opioid abstinence reinforcement delays heroin lapse during buprenorphine dose tapering.

Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan 48207, USA.
Journal of Applied Behavior Analysis (Impact Factor: 1.19). 02/2008; 41(4):603-7. DOI: 10.1901/jaba.2008.41-603
Source: PubMed

ABSTRACT A positive reinforcement contingency increased opioid abstinence during outpatient dose tapering (4, 2, then 0 mg/day during Weeks 1 through 3) in non-treatment-seeking heroin-dependent volunteers who had been maintained on buprenorphine (8 mg/day) during an inpatient research protocol. The control group (n=12) received $4.00 for completing assessments at each thrice-weekly visit during dose tapering; 10 of 12 lapsed to heroin use 1 day after discharge. The abstinence reinforcement group (n=10) received $30.00 for each consecutive opioid-free urine sample; this significantly delayed heroin lapse (median, 15 days).

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May 22, 2014