Fast Disinfecting Antimicrobial Surfaces

Department of Polymer Science & Engineering, University of Massachusetts, Amherst, Massachusetts 01003, USA.
Langmuir (Impact Factor: 4.38). 02/2009; 25(2):1060-7. DOI: 10.1021/la802953v
Source: PubMed

ABSTRACT Silicon wafers and glass surfaces were functionalized with facially amphiphilic antimicrobial copolymers using the "grafting from" technique. Surface-initiated atom transfer radical polymerization (ATRP) was used to grow poly(butylmethacrylate)-co-poly(Boc-aminoethyl methacrylate) from the surfaces. Upon Boc-deprotection, these surfaces became highly antimicrobial and killed S. aureus and E. coli 100% in less than 5 min. The molecular weight and grafting density of the polymer were controlled by varying the polymerization time and initiator surface density. Antimicrobial studies showed that the killing efficiency of these surfaces was independent of polymer layer thickness or grafting density within the range of surfaces studied.


Available from: Ahmad E Madkour, Nov 15, 2014
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