Psoriatic arthritis is a strong predictor of sleep interference in patients with psoriasis
ABSTRACT We sought to determine what clinical features of psoriasis predict sleep interference.
Data were obtained from 420 respondents to the 2005 National Psoriasis Foundation telephone and e-mail surveys. Logistic regression was used to determine whether disease severity, body mass index, age of onset, psoriatic arthritis, income, ethnicity, sex, current therapy, and quality-of-life measures predicted reported sleep interference within the last month.
Psoriatic arthritis was the most significant predictor of sleep disturbance (odds ratio = 3.26). Itch, pain of lesions, and impact on emotional well-being were also significant predictors (odds ratio 1.26, 1.22, and 1.18, respectively). Body surface area covered with psoriasis, body mass index, and therapy were not significant predictors of sleep interference.
All data were self-reported and not physician-assessed.
History of psoriatic arthritis, presence of itch and pain of psoriatic lesions, and impact of psoriasis on overall emotional well-being predict sleep interference.
SourceAvailable from: Mybera Ferizi[Show abstract] [Hide abstract]
ABSTRACT: Steatocystoma multiplex is primarily an inherited condition:however many cases have been reported where there is no apparent inheritance pattern. This desease is characterized yellow to white papules and cysts that tend to develop on the arms, chest, axillae, neck and scrotum..They can range in size from 2mm to 2cm.When squeezed the cysts exude a yellow to white tenacious fluid. Treatment for lesions has included surgical excision or drainage,oral retinoids and liquid nitrogen cryotherapy. Key words: Polycystic Disease. dermal cysts, Steatocystoma multiplex.Medicus 06/2006; V((1)):107-110.
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ABSTRACT: The scalp is frequently affected in psoriasis patients, and pruritus can adversely affect the quality of life of affected patients. Few studies have assessed pruritus in scalp psoriasis. To determine the correlation among the clinical characteristics of pruritus, psoriasis scalp severity index (PSSI), and intraepidermal nerve fiber (IENF) density in psoriatic scalp lesions. Eighty patients (53 men, 27 women; mean age, 46.4 years; mean PSSI, 19.9) with scalp psoriasis were evaluated by using the PSSI and the Leuven itch scale. Biopsies were obtained from the lesional and nonlesional skin of 19 patients (10 men, 9 women; mean age, 37.8 years; mean PSSI, 25.8). Immunofluorescence staining of protein gene product 9.5 was performed to determine the IENF density. Sixty-four patients (80%) complained of pruritus associated with scalp psoriasis, which negatively affected their quality of life to varying degrees. A moderate positive relation between PSSI score and pruritus intensity was identified (r=0.225 and p=0.044). The IENF density in psoriatic lesions was significantly higher than that in the nonlesional scalp (6.2±1.2 vs. 4.2±1.6, p<0.001). However, the correlations between IENF density and PSSI score, and IENF density and pruritus intensity were insignificant. These results indicate that pruritus prevalence is high in patients with scalp psoriasis, and pruritus considerably influences the patients' daily lives and quality of life. In addition, high IENF density in psoriatic scalp lesions may play a role in the development of pruritus in scalp psoriasis.Annals of Dermatology 12/2014; 26(6):727-732. DOI:10.5021/ad.2014.26.6.727 · 0.95 Impact Factor
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ABSTRACT: ABSTRACT Psoriasis is a chronic skin disorder that affects 1% to 3% of the world's population. Psoriasis is a noncontagious common skin condition that causes rapid skin cell reproduction resulting in red, dry patches of thickened skin. The dry flakes and skin scales are thought to result from the rapid buildup of skin cells. The exact cause of psoriasis is unknown, but most researchers believe that a combination of several factors contributes to the development of this disease. Psychological stress has long been understood as a trigger for psoriasis flares, but scientists are still unclear about exactly how this occurs. The cause of stress varies in each person. Stress could be caused by nature of work, state of finances, family worries. In some cases even positive developments such as marriage or child birth can cause stress and lead to Psoriasis. The aim of our study was to compare the impact of stressful life during the war period as the cause of manifestation of psoriasis in the years 1999-th and post-war period in the 2009-th.