Article

Dispersive liquid-liquid microextraction combined with high-performance liquid chromatography-UV detection as a very simple, rapid and sensitive method for the determination of bisphenol A in water samples.

Department of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
Journal of Chromatography A (Impact Factor: 4.61). 02/2009; 1216(9):1511-4. DOI: 10.1016/j.chroma.2008.12.091
Source: PubMed

ABSTRACT Dispersive liquid-liquid microextraction (DLLME) coupled with high-performance liquid chromatography (HPLC)-UV detection was applied for the extraction and determination of bisphenol A (BPA) in water samples. An appropriate mixture of acetone (disperser solvent) and chloroform (extraction solvent) was injected rapidly into a water sample containing BPA. After extraction, sedimented phase was analyzed by HPLC-UV. Under the optimum conditions (extractant solvent: 142 microL of chloroform, disperser solvent: 2.0 mL of acetone, and without salt addition), the calibration graph was linear in the range of 0.5-100 microgL(-1) with the detection limit of 0.07 microgL(-1) for BPA. The relative standard deviation (RSD, n=5) for the extraction and determination of 100 microgL(-1) of BPA in the aqueous samples was 6.0%. The results showed that DLLME is a very simple, rapid, sensitive and efficient analytical method for the determination of trace amount of BPA in water samples and suitable results were obtained.

0 Bookmarks
 · 
84 Views
  • [Show abstract] [Hide abstract]
    ABSTRACT: A new extraction method, based on Dispersive Nano-Solid material-Ultrasound Assisted Micro-Extraction (DNSUAME), was used for the preconcentration of the bendiocarb and promecarb pesticides in the water samples prior to high performance liquid chromatography (HPLC). The properties of NiZnS nanomaterial loaded on activated carbon (NiZnS-AC) are characterized by FT-IR, TEM, and BET. This novel nanomaterial showed great adsorptive ability towards the bendiocarb and promecarb pesticides. The effective variables such as the amount of adsorbent (mg: NiZnS-AC), the pH and ionic strength of sample solution, the vortex and ultrasonic time (min), the ultrasonic temperature (°C), and desorption volume (mL) are investigated by screening 2(7-4) experiments of Plackett-Burman (PB) design. The important variables optimized by using a central composite design (CCD) were combined by a desirability function (DF). At optimum conditions, the method has linear response over 0.0033-10µgmL(-1) with detection limit between 0.0010 and 0.0015µgmL(-1) with relative standard deviations (RSDs) less than 5.5% (n=3). The method has been successfully applied for the determination of the bendiocarb and promecarb pesticides in the water samples.
    Talanta 11/2013; 116:637-46. · 3.50 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: A method of ultrasound-dispersive liquid-liquid microextraction (US-DLLME) combined with high-performance liquid chromatography/variable wavelength detection (HPLC-VWD) has been developed for rapid measuring tetrabromobisphenol A and its five derivatives in water. Parameters affecting the extraction efficiency including the extraction solvents and dispersive solvents and their volume, ionic strength of the sample, and ultrasound time were optimized, and further validated by orthogonal array design (OAD). The optimized conditions provided enrichment factors for analytes of 74-490. Most analytes had linear responses between 2 and 500μgL(-1), with correlation coefficients (r(2)) of 0.9923-0.9994. Limits of detection were 0.13-0.63μgL(-1). Relative standard deviations (RSDs) for five replicates ranged from 2.6% to 4.5% for all analytes. When applied to spiked samples of real water, the method provided recoveries of 88.6-106.3% for tap water, 87.8-108.5% for Mi River water, 82.7-113.5% for chemical wastewater, 45.5-115.3% for urine, and 46.4-126.2% for fruit juice, with RSDs (n=5) less than 4%, 6%, 8%, 10%, and 9% respectively.
    Talanta 11/2013; 116:906-11. · 3.50 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: A new spectrophotometric method for the determination of trace amounts of bisphenol A based on a diazotization-coupling reaction was developed. In acidic solution, clenbuterol was first diazotized with sodium nitrite, then coupled with bisphenol A to from an azo-compound [I] in NH3-NH4Cl buffer, which shows a maximum absorption at 410nm. The effects of the amount of sodium nitrite, diazo reaction time, the amount of clenbuterol, coupling reaction time and coupling reaction temperature have been examined. Under the optional conditions, the determination of the linear range of bisphenol A is 0.24-8.4μg/mL, correlation coefficient is 0.9905 and detection limit of this method is 0.15μg/mL. The spectrophotometric method is simple, rapid, high sensitivity with better accuracy. High performance liquid chromatography (HPLC) technique combined with this new spectrophotometric method has been also developed for the measurement of bisphenol A. The analysis was achieved on a C18 column using water and methanol as a mobile phase and the detection was done spectrophotometrically at 410nm. These reported methods were applied to the determination of bisphenol A in hot water in contact with commercially available table-water bottle samples.
    Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy 11/2013; 122C:153-157. · 1.98 Impact Factor

Full-text

View
66 Downloads
Available from
Jun 5, 2014