Dispersive liquid-liquid microextraction combined with high-performance liquid chromatography-UV detection as a very simple, rapid and sensitive method for the determination of bisphenol A in water samples.

Department of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
Journal of Chromatography A (Impact Factor: 4.61). 02/2009; 1216(9):1511-4. DOI: 10.1016/j.chroma.2008.12.091
Source: PubMed

ABSTRACT Dispersive liquid-liquid microextraction (DLLME) coupled with high-performance liquid chromatography (HPLC)-UV detection was applied for the extraction and determination of bisphenol A (BPA) in water samples. An appropriate mixture of acetone (disperser solvent) and chloroform (extraction solvent) was injected rapidly into a water sample containing BPA. After extraction, sedimented phase was analyzed by HPLC-UV. Under the optimum conditions (extractant solvent: 142 microL of chloroform, disperser solvent: 2.0 mL of acetone, and without salt addition), the calibration graph was linear in the range of 0.5-100 microgL(-1) with the detection limit of 0.07 microgL(-1) for BPA. The relative standard deviation (RSD, n=5) for the extraction and determination of 100 microgL(-1) of BPA in the aqueous samples was 6.0%. The results showed that DLLME is a very simple, rapid, sensitive and efficient analytical method for the determination of trace amount of BPA in water samples and suitable results were obtained.

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Jun 5, 2014