"Researchers at Vanderbilt University published a study in the New England Journal of Medicine suggesting a new risk: sudden heart failure. The investigators found three cardiac deaths per year for every 1,000 patients taking anti-psychotic drugs like Seroquel (Schneeweiss and Avorn, 2009). One of the most radical pharmaceutical treatments for PTSD is the street drug Ecstasy, or methylenedioxymethamphetamine (MDMA). "
[Show abstract][Hide abstract] ABSTRACT: A review of clinical evidence and neurobiology on the effects of modulation of sympathetic system modulation to treat post-traumatic stress disorder (PTSD) is being presented . The review provides an overview of currently available treatments followed by efficacy of orally effective sympathetic blocking agents. The main focus of the review is the application of stellate ganglion blocks (SGBs) or a local anesthetic blockade of the sympathetic ganglion in the neck.
"There is also the spectre of adverse sequelae of treatment with some antipsychotic medications, including psychotropicrelated metabolic disturbance (including weight gain, hyperlipidaemia and diabetes), leading to potential early death (Buckley et al. 2008). Most recently, findings of an excess of sudden cardiac death associated with antipsychotics has led to caution being advocated about the over-liberal use of such drugs (Schneeweiss & Avorn, 2009). "
[Show abstract][Hide abstract] ABSTRACT: This paper reviews the literature on early intervention in psychotic disorders, weighs the cons of this approach, and makes suggestions for clinicians and researchers regarding how to interpret and respond to what is still an embryonic evidence-base, notably in terms of any long-term benefits.
Psychological Medicine 03/2010; 40(3):353-8. DOI:10.1017/S0033291709990341 · 5.94 Impact Factor
"Although the evidence that is available thus far is not consistent, this review gives some support to the hypothesis that long-term exposure to antipsychotics increases mortality in schizophrenia. Some psychiatrists who acknowledge that death can result from taking antipsychotics may nevertheless argue that in patients " for whom the drug is truly indicated, a small risk of rare but fatal side effects may be acceptable until new medications with a safer cardiac risk profile are developed " (Schneeweiss and Avorn, 2009 "
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.