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Limited utility of serum galactomannan assay after auto-SCT.

1From the Infectious Disease Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Bone marrow transplantation (Impact Factor: 3.47). 02/2009; 44(1):59-61. DOI: 10.1038/bmt.2008.425
Source: PubMed
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    ABSTRACT: The human immune system is capable of recognizing and degrading chitin, an important cell wall component of pathogenic fungi. In the context of host-immune responses to fungal infections, herein we review the particular contributions and interplay of fungus and chitin recognition, and chitin-degrading enzymes, known as chitinases. The mechanisms of host chitinase responses may have implications for diagnostic assays as well as novel therapeutic approaches for patients that are at risk of contracting fatal fungal infections.
    International Journal of Microbiology 01/2012; 2012:920459. DOI:10.1155/2012/920459

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