Article

Expanding roles for SREBP in metabolism

Department of Cell Biology, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA.
Cell Metabolism (Impact Factor: 16.75). 10/2012; 16(4):414-419. DOI: 10.1016/j.cmet.2012.09.002.

ABSTRACT Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular lipogenesis and lipid homeostasis. Recent studies reveal expanding roles for SREBPs with the description of new regulatory mechanisms, the identification of unexpected transcriptional targets, and the discovery of functions for SREBPs in type II diabetes, cancer, immunity, neuroprotection, and autophagy.

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Available from: Wei Shao, Jul 05, 2015
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