Article

Isolated tuberculosis of the pancreas: a case report.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
JOP: Journal of the pancreas 02/2009; 10(1):64-6. pp.64-6
Source: PubMed

ABSTRACT Pancreatic tuberculosis is a rare entity. Only a few cases have been reported in the medical literature. We hereby describe a case of pancreatic tuberculosis in an immunocompromized individual.
A fifty-year-old African-American gentleman with history of HIV non-compliant on anti-retroviral therapy presented with epigastric pain for five weeks duration. CT scan of abdomen showed large necrotic node on the posterior aspect of the head of pancreas and multiple cystic masses adjacent to the pancreas. Acid fast bacilli were found on staining of CT guided biopsy of the node. Cultures grew Mycobacterium tuberculosis. Anti-tubercular therapy was initiated and resulted in gradual resolution of symptoms.
Pancreatic tuberculosis is rare and is frequently confused with pancreatic cancer on clinical presentation as well as on imaging studies. Since it is a curable disease, accurate diagnosis is paramount CT or ultrasound guided biopsy is cornerstone of diagnosis. Endoscopic ultrasound is now increasingly being used for obtaining tissue for diagnosis. Anti-tubercular therapy is curative in majority of the cases.

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Keywords

accurate diagnosis
 
Acid fast bacilli
 
anti-retroviral therapy
 
cases
 
clinical presentation
 
CT scan
 
fifty-year-old African-American gentleman
 
gradual resolution
 
HIV non-compliant
 
imaging studies
 
immunocompromized individual
 
large necrotic node
 
medical literature
 
multiple cystic masses adjacent
 
Mycobacterium tuberculosis
 
pancreatic cancer
 
Pancreatic tuberculosis
 
staining
 
weeks duration
 

Shyam Dang