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Quantitative matrix-assisted laser desorption/ionization mass spectrometry

Division of Endocrinology, Metabolism and Diabetes, School of Medicine, University of Colorado Denver, Mail Stop 8106, 12801 East 17th Avenue, Aurora, CO 80045, USA.
Briefings in Functional Genomics and Proteomics 10/2008; 7(5):355-370. DOI: 10.1093/bfgp/eln041
Source: PubMed

ABSTRACT This review summarizes the essential characteristics of matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry (TOF MS), especially as they relate to its applications in quantitative analysis. Approaches to quantification by MALDI-TOF MS are presented and published applications are critically reviewed.

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