Squamous cell carcinoma of the breast: A case report

Deventer Hospital, Department of Surgery, Postbus 5001, 7400 GC Deventer, the Netherlands.
World Journal of Surgical Oncology (Impact Factor: 1.41). 01/2009; 6(1):135. DOI: 10.1186/1477-7819-6-135
Source: PubMed


Squamous cells are normally not found inside the breast, so a primary squamous cell carcinoma of the breast is an exceptional phenomenon. There is a possible explanation for these findings.
A 72-year-old woman presented with a breast abnormality suspected for breast carcinoma. After the operation the pathological examination revealed a primary squamous cell carcinoma of the breast.
The presentation of squamous cell carcinoma could be similar to that of an adenocarcinoma. However, a squamous cell carcinoma of the breast could also develop from a complicated breast cyst or abscess. Therefore, pathological examination of these apparent benign abnormalities is mandatory.

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Available from: Elvira R Flikweert, Dec 26, 2013
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    • "According to our search in the world literature, only some series are reported.[4] The incidence of the primary SCC among all the breast carcinomas is approximately between of 0.1% to less than 0.04%.[56] "
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    ABSTRACT: In females, the most common cancer is breast carcinoma in which squamous cell carcinoma (SCC) is a rare type of malignancy. Histologically, infiltrating ductal carcinoma is the most common type and lobular, mucinous, and medullary types have lower incidence. Pure SCC of the breast can originate from the skin, nipple, or epithelium of a deep-seated dermoid cyst or squamous metaplasia on chronic inflammation background. We are reporting a rare case of primary SCC of the breast in a 45-year-old female. In follow-up of 8 months, patient is doing well. We discussed our approach for treatment with review of the literature. We have treated this patient successfully with surgical and adjuvant chemotherapy.
    International journal of preventive medicine 07/2013; 4(7):845-8.
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    • "Squamous cell cancer of the breast (SCCB) is extremely a rare malignancy. The diagnosis of primary squamous cell cancer is made when the malignant cells are entirely of squamous type and the adjoining breast malignancy or other sites of squamous cell cancer have been excluded [5]. These tumors are reported to be aggressive and have poor prognosis. "
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    ABSTRACT: Primary squamous cell carcinoma of the breast (SCCB) is a very rare malignancy of the breast and is generally aggressive. It is even rarer during the gestational period. Only few cases have been reported during pregnancy and lactation (Rokutanda et al., 2000). SCCB seen within the gestational period tends to be very aggressive and has a larger size than other breast carcinomas. Pure SCCB is derived from the epidermis of the breast, nipple, or metaplasia on chronic inflammatory background (Bige et al., 2007), such as complicated breast cyst, dermoid cyst, or abscess. We report a case of SCCB in a 30-year-old primigravida that had an aggressive propensity and fatal outcome.
    Case Reports in Medicine 12/2011; 2011:327029. DOI:10.1155/2011/327029
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