Parental Psychopathology and Offspring Suicidality in Mexico

a National Institute of Psychiatry, Col. San Lorenzo Huipulco , Mexico City , Mexico.
Archives of suicide research: official journal of the International Academy for Suicide Research 04/2013; 17(2):123-35. DOI: 10.1080/13811118.2013.776449
Source: PubMed


The objective of this study was to estimate the extent to which parental psychopathology may confer increased risk of suicide ideation and attempts among their offspring in Mexico. Data from a representative sample of 5,782 respondents participating in the Mexican National Comorbidity Survey (2001-2002) to examine the unique associations between parental psychopathology and offspring suicidality were used. Parental disorders (major depression, panic disorder, generalized anxiety disorder, substance dependence, and antisocial personality disorder) were comorbid and after controlling for comorbidity and number of disorders only parental panic and antisocial personality disorder remained associated with ideation and attempts in the total sample. Those with more parental disorders were at increased risk of ideation and attempt, as well as increased risk to transition from suicide ideation to an attempt. These findings may help inform clinical and public health efforts aimed at suicide prevention in Mexico and other developing countries.

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    • "In particular, the familial transmission of an adverse family environment, imitation, or bereavement could be related to heritable risk factors [8]. Interestingly, it was reported that suicide ideation and attempts were strongly associated with parental psychopathology [9] [10]. In addition, it has been suggested that certain personality traits may predispose to affective disorders and suicidal behavior [11]. "
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    ABSTRACT: Personality traits are important candidate predictors of suicidal behavior. Several studies have reported an association between personality/temperament traits and suicidal behavior, suggesting personality traits as intermediary phenotypes related to suicidal behavior. Thus, it is possible that suicide attempts can be accounted for by increased familial rates of risk personality traits. The aim of this work was to evaluate personality traits in affective disorder patients with attempted suicide and to compare them with the personality trait scores of their parents. In addition, ITC scores in the two groups were compared with a healthy control sample. The patients evaluated met the DSM-IV criteria for major depression disorder or dysthymia and had a documented history of suicide attempts. Psychiatric diagnoses of patients and parents were done according to the SCID-I and the personality was assessed using the Temperament and Character Inventory. We analyzed 49 suicide attempt subjects and their parents (n = 95) and 89 control subjects. We observed that temperament and character dimensions were similar between patients and their parents (P > 0.05). In particular, we observed that high HA and low P, SD, and CO were shared among families. Our study is the first to report that the personality traits of affective disorder patients with a history of attempted suicide are shared between patients and their parents.
    Depression research and treatment 03/2014; 2014:291802. DOI:10.1155/2014/291802
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    ABSTRACT: Little is known about the epidemiology of suicide attempts among psychiatric outpatients in Mexico. This study was aimed to determine the socio-demographic, clinical and behavioral characteristics associated with suicide attempts in psychiatric outpatients in two public hospitals in Durango, Mexico. Two hundred seventy six psychiatric outpatients (154 suicide attempters and 122 patients without suicide attempt history) attended the two public hospitals in Durango City, Mexico were included in this study. Socio-demographic, clinical and behavioral characteristics were obtained retrospectively from all outpatients and compared in relation to the presence or absence of suicide attempt history. Increased prevalence of suicide attempts was associated with mental and behavioral disorders due to psychoactive substance use (F10-19) (P=0.01), schizophrenia, schizotypal and delusional disorders (F20-29) (P=0.02), mood (affective) disorders (F30-39) (P<0.001), and disorders of adult personality and behavior (F60-69) (P<0.001). Multivariate analysis showed that suicide attempts were associated with young age (OR=1.21, 95% CI: 1.06-1.39; P=0.003), female gender (OR=2.98, 95% CI: 1.55-5.73; P=0.001), urban residence (OR=2.31, 95% CI: 1.17-4.57; P=0.01), memory impairment (OR=1.91, 95% CI: 1.07-3.40; P=0.02), alcohol consumption (OR=2.39, 95% CI: 1.21-4.70; P=0.01), and sexual promiscuity (OR=3.90, 95% CI: 1.74-8.77; P<0.001). We report the association of suicide attempts with socio-demographic, clinical and behavioral characteristics in psychiatric outpatients in Mexico. Results may be useful for an optimal planning of preventive measures against suicide attempts in psychiatric outpatients.
    03/2014; 10(1):61-8.
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    ABSTRACT: We review research on the relationship of exposure to psychological trauma, with non-suicidal self-injury (NSSI) and suicidality (suicidal ideation [SI], and suicide attempts [SA]) in individuals with dissociative disorders and posttraumatic stress disorder (PTSD). The review provides a context for the Special Issue of the Journal of Trauma and Dissociation on these topics. Exposure to childhood sexual abuse was the most consistent traumatic antecedent of self-harm, although traumatic violence in childhood (particularly physical abuse) and adulthood (particularly domestic violence) and exposure to multiple types of traumatic stressors also were associated with NSSI and SI/SA. Dissociative disorders and PTSD are consistently associated with increased NSSI and SA/SI. There is preliminary cross-sectional evidence that dissociation and posttraumatic stress disorders may mediate the relationship between psychological trauma and NSSI and SI/SA. Research on emotion dysregulation as a potential cross-cutting mechanism linking dissociation, PTSD, and self-harm is also reviewed. We conclude with discussion of implications for clinical practice and future directions for scientific research.
    Journal of Trauma & Dissociation 03/2015; 16(3). DOI:10.1080/15299732.2015.989563 · 1.72 Impact Factor
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