Article

Effect of short term administration of cinnamon on blood pressure in patients with pre and type 2 diabetes

Nutrition (Impact Factor: 2.86). 05/2013;

ABSTRACT Objective:
To systematically review and evaluate the effect of short term administration of cinnamon on blood pressure regulation in pre and type 2 diabetes patients by performing a meta-analysis of randomized placebo-controlled clinical trials.

Research Methods and Procedures:
Medical literature for randomized controlled trials (RCTs) of the effect of cinnamon on blood pressure was systematically searched; 3 original articles published from January 2000 to September 2012 were identified from the MEDLINE database and a hand search of the reference lists of the articles obtained through MEDLINE. The search terms included cinnamon or blood pressure or systolic blood pressure (SBP) or diastolic blood pressure (DBP) or diabetes. A random effects model was used to calculate weighted mean difference and 95% confidence intervals (CI).

Results:
The pooled estimate of the effect of cinnamon intake on systolic and diastolic blood pressure demonstrated that the use of cinnamon significantly decreased SBP and DBP by 5.39 mmHg (95% CI: -6.89, -3.89) and 2.6 mmHg (95% CI: - 4.53, -0.66) respectively.

Conclusion:
Consumption of cinnamon (short term) is associated with notable reduction of SBP and DBP. Although cinnamon shows hopeful effects on blood pressure lowering potential, it would be premature to recommend cinnamon for blood pressure control, because of the limited number of studies available. Thus, undoubtedly a long term, adequately powered RCTs involving a larger number of patients is needed to appraise the clinical potential of cinnamon on blood pressure control among patients with type 2 diabetes mellitus.

Key words: Blood pressure, Diabetes, Cinnamon, Blood glucose, randomized control trials.

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