"Formalin is an effective tuberculocidal but a granuloma , a mass of inflamed granulation tissue, can deter the penetration of embalming fluid into these sites (Best et al., 1990; Demiry € urek et al., 2002; Nemec et al., 2013). MTB is an aerobic bacterium and therefore proliferates in areas of a high oxygen tension such as the lung apex (Nemec et al., 2013). There also seem to be a lack of guidelines for the effective and safe handling of formalin-fixed autopsy tissue that has been infected by MTB. "
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