Clinical Outcomes Associated With Procalcitonin Algorithms to Guide Antibiotic Therapy in Respiratory Tract Infections

Medical University Department, Kantonsspital Aarau, Tellstrasse, CH-5001 Aarau, Switzerland.
JAMA The Journal of the American Medical Association (Impact Factor: 35.29). 02/2013; 309(7):717-8. DOI: 10.1001/jama.2013.697
Source: PubMed


Clinical question:
In patients with respiratory tract infection, is measurement of procalcitonin to guide antibiotic prescriptions associated with reduced antibiotic exposure without increases in all-cause mortality or treatment failure?

Bottom line:
The measurement of procalcitonin to guide initiation and duration of antibiotic treatment in patients with respiratory tract infections of varying severity is associated with lower antibiotic exposure without increasing all-cause mortality or treatment failure.


Available from: Beat Müller, Jan 18, 2014
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