Función cognitiva en pacientes diabetes mellitus tipo 2.

Med Int Mex 09/2011; 27(5):217-223.


Background: Cognitive decline in diabetes mellitus type 2 is well recognized; its etiology is complex due to the diversity of physiopathologic mechanisms potentially involved as well as the high prevalence of comorbility including hypertension, obesity and dyslipidemia. Material and Method: In the review we present recent evidence regarding risk factors related with congnitive decline in diabetic population. Risk factors reviewed included glycemic control, insulin resistance but also obesity, hypertension and metabolic syndrome. Results: Cognitive decline in diabetic patients appear to be mainly related with glycemic control.
Conclusion: Current evidence suggests a multifactorial etiology with uncontrolled chronic glycemia and HbA1c as a marker standing out. Nevertheless, an integral treatment of comorbilities and regular evaluations of cognitive function are required.

Download full-text


Available from: Mayela Rodríguez-Violante,