Qualitative human immunodeficiency virus RNA analysis of dried blood spots for diagnosis of infections in infants.

Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, 11-141 Lineberger Cancer Center, CB 7295, Chapel Hill, NC 27599, USA.
Journal of clinical microbiology (Impact Factor: 4.23). 12/2008; 47(1):220-2. DOI: 10.1128/JCM.01521-08
Source: PubMed

ABSTRACT The Gen-Probe Aptima human immunodeficiency virus type 1 (HIV-1) RNA assay was adapted for the diagnosis of HIV infection in infants by using dried blood spots. The assay was 99% sensitive (128/129) and 100% specific (162/162). This may prove useful in resource-limited settings, since it precludes the need for a phlebotomist and maintenance of a cold chain.

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    Journal of clinical virology: the official publication of the Pan American Society for Clinical Virology 06/2014; 60(4). DOI:10.1016/j.jcv.2014.05.012 · 3.12 Impact Factor
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    The American journal of tropical medicine and hygiene 12/2013; 90(2). DOI:10.4269/ajtmh.13-0463 · 2.53 Impact Factor


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