Article

Corneal and conjunctival epithelial staining in hydrogel contact lens wearers.

Unit of Optometry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Eye & contact lens 12/2008; 34(6):312-6. DOI:10.1097/ICL.0b013e3181891439
Source: PubMed

ABSTRACT The purpose of this study was to investigate the prevalence of conjunctival and corneal epithelial staining in soft contact lens wearers and to see if staining could be associated with factors such as type of lens worn, wearing time, care system, age, and sex.
The records of 338 adapted hydrogel contact lens wearers were examined retrospectively.
Conjunctival staining was found to be present in 32.5% of the subjects and corneal staining was found to be present in 19.5% of subjects. None of the subjects had staining above grade 2 using the Cornea and Contact Lens Research Unit scale. Because of the low prevalence of staining, the low grading of staining found and the large variation in refractive power, lens type worn, wearing modality, and solution used statistical analysis for association between staining and different factors could only be performed for the association between sex and staining and between corneal and conjunctival staining. However, no statistical significant association could be demonstrated.
Despite the low prevalence of staining the conjunctiva and cornea should be examined carefully in contact lens wearers and prospective wearers because the conjunctival and corneal epithelium serve as protective barriers for the underlying layers of the cornea and conjunctiva. To allow comparison of data obtained in different studies assessing corneal staining, it is recommended that clinicians develop and adopt a universal standard protocol for this measure.

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Keywords

conjunctival
 
conjunctival staining
 
Contact Lens Research Unit scale
 
contact lens wearers
 
Cornea
 
corneal
 
corneal epithelial staining
 
corneal epithelium
 
corneal staining
 
different factors
 
hydrogel contact lens wearers
 
large variation
 
lens type
 
low grading
 
low prevalence
 
prospective wearers
 
refractive power
 
soft contact lens wearers
 
statistical significant association
 
universal standard protocol