Article

Transcatheter arterial embolization in gastric cancer patients with acute bleeding.

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-gu, Seoul, Korea.
European Radiology (impact factor: 3.22). 12/2008; 19(4):960-5. DOI:10.1007/s00330-008-1216-2 pp.960-5
Source: PubMed

ABSTRACT The safety and clinical effectiveness of transcatheter arterial embolization for bleeding associated with unresectable gastric cancer was evaluated. Twenty-three patients with bleeding from unresectable gastric cancer underwent transcatheter arterial embolization. Of the 23 patients, eight showed signs of active bleeding, such as contrast extravasation or pseudoaneurysm, seven showed only tumor staining, and the remaining eight patients showed negative angiographic findings. All embolization procedures were successful without procedure-related complications. In all eight active bleeding patients, immediate hemostasis was achieved. The overall clinical success rate was 52% (12/23). Recurrent bleeding within 1 month occurred in one (8%) in 12 patients with initial clinical success. One patient showed partial splenic infarction after embolization of the splenic artery for active bleeding from the short gastric artery. Overall 30-day mortality rate was 43% (10/23). The median overall survival period was 38 days. In patients with bleeding from unresectable gastric cancer, transcatheter arterial embolization was found to be safe and effective for achieving immediate hemostasis for active bleeding. Although the clinical success rate was not high, the recurrent bleeding rate was low at 1 month post procedure.

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Keywords

1 month
 
1 month post procedure
 
12 patients
 
23 patients
 
30-day mortality rate
 
clinical effectiveness
 
clinical success rate
 
contrast extravasation
 
eight active
 
embolization procedures
 
immediate hemostasis
 
initial clinical success
 
negative angiographic findings
 
partial splenic infarction
 
procedure-related complications
 
remaining eight patients
 
signs
 
transcatheter arterial embolization
 
tumor staining
 
unresectable gastric cancer
 

Hyun Lee