Article

Autism: Many Genes, Common Pathways?

Neurogenetics Program, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Cell (Impact Factor: 31.96). 11/2008; 135(3):391-5. DOI: 10.1016/j.cell.2008.10.016
Source: PubMed

ABSTRACT Autism is a heterogeneous neurodevelopmental syndrome with a complex genetic etiology. It is still not clear whether autism comprises a vast collection of different disorders akin to intellectual disability or a few disorders sharing common aberrant pathways. Unifying principles among cases of autism are likely to be at the level of brain circuitry in addition to molecular pathways.

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